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Features

EpiGenie Features call out new Methods, provide Insights into emerging trends, or sometimes just share technical tips from the experts in our community.

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EpiGenie Reviews RNA and the Regulation of Gene Expression

February 1, 2012

The concept of gene regulation by RNAs wasn’t always as well accepted as it is today, and even now some view the idea as controversial. The text RNA and the Regulation of Gene Expression, edited by Kevin Morris, explores the evidence that has convinced many top researchers of the important roles that RNAs have in […]

Getting Down to Histone Antibody Specifics

December 15, 2011

Histone antibody specificity has been the topic of publications as well as discussions at meetings and conferences (probably water coolers and coffeemakers, too) within scientific community recently. Clearly, antibody specificity is important to researchers, but what are vendors doing to address it? To get an idea of what goes into making better histone antibodies we […]

5fC & 5caC Follow Up Strong in 5hmC Sequel

December 14, 2011

Life was simpler back when there were only four bases. Nowadays researchers studying DNA methylation have to keep track of four methylCytosine derivatives alone, and the research is just starting to heat up. The last couple of years the TET family of proteins has proven effective at catalyzing 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), apparently as […]

Profiling Exon Methylation with Liquid Hybridization Capture-Based Bisulfite Sequencing

December 12, 2011

Sometimes, you just want to get to the good stuff right away. Now, researchers in China report that they’ve developed a way to target their sequencing when analyzing methylomes rather juggling 6 hard drives. With their new liquid hybridization capture-based bisulfite sequencing (LHC-BS) method, they just grab exons and analyze them for methylation. The method […]

DNA Methylation Changes in Cancer

October 29, 2011

EpiGenie ran recently ran a review of the new text Epigenetics: A Reference Manual. Now, to present a little taste of what the book has to offer, here’s a summary of one of the chapters. DNA Methylation Changes in Cancer By Samson Mani and Zdenko Herceg Epigenetic mechanisms can contribute to each step of cancer […]

Macrosatellite Epigenetics

October 28, 2011

EpiGenie ran recently ran a review of the new text Epigenetics: A Reference Manual. Now, to present a little taste of what the book has to offer, here’s a summary of one of the chapters. Macrosatellite Epigenetics By Brian P. Chadwick The sequence of the human genome does not differ considerably from that of other […]

Imprinted Brain Theory with Dr Christopher Badcock

September 13, 2011

Dr. Christopher Badcock explains key epigenetic concepts of the Imprinted Brain theory and how it might change the way we think about mental disorders. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. Imprinted Brain Theory Well, […]

DNA Methylation in Stem Cell Pluripotency with Dr Louise Laurent

September 13, 2011

Dr. Louise Laurent discusses DNA methylation patterning in the pluripotent state. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. This video was made possible by epigenetics supporters at Zymo Research. DNA Methylation in Stem Cell Pluripotency So […]

Epigenetics in Autism-Spectrum Disorders with Dr Janine LaSalle

September 13, 2011

Dr. Janine LaSalle covers the epigenetics involved in autism-spectrum disorders. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. Epigenetics in Autism-Spectrum Disorders I’ll start with saying I kind of joked that I’ve been in epigenetics before […]

Bisphenol A (BPA) and the Epigenome with Dr Dana Dolinoy

September 13, 2011

Dr. Dana Dolinoy discusses how early life exposures to environmental exposures like bisphenol A can impact the epigenome. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. This video was made possible by support from epigenetics fans […]

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