Prenatal Environmental Exposures, Epigenetics, and Health with Dr Frederica PereraSeptember 9, 2011Dr. Frederica Perera touches on how the environment around us can make a big impact very early in life and stick with us for a long time. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. Environmental Exposures […]
Human Transgenerational Responses with Dr Marcus PembreySeptember 9, 2011Dr. Marcus Pembrey provides a nice background on his experiences with imprinting and how it might provide a means for transgenerational adaptation. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. Interview Transcript I’m a chemical geneticist, […]
Imprinted Genes and Fetal Growth with Dr Gudrun MooreSeptember 8, 2011Dr. Gudrun Moore discusses her studies of key genes involved with fetal growth and their regulation. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. Imprinted Genes and Fetal Growth As I am fundamentally interested in looking […]
Early-Life Stress, Epigenetics, and Disease with Dr Patrick McGowanSeptember 8, 2011Dr. Patrick McGowan discusses how stresses early in life can potentially impact epigenetic mechanisms and disease susceptibility. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. Environmental Influences on Developmental Programming Well epigenetics is really central to the […]
NCBI NIH Tools for Surfing the EpigenomeAugust 31, 2011Massive epigenome mapping projects have led to a deluge of data that eager epigeneticists can’t wait dive into, but it’s not quite that simple. It’s no easy feat to learn about the best places to download, view or manipulate epigenomic data, much less understand the tidal wave of information once you’ve found it. It’s all […]
A New Spin on RNA PurificationAugust 18, 2011RNA isolation. It doesn’t get that much hype, but it should considering it’s the first, and perhaps most critical, step in virtually every RNA analysis workflow out there. Today’s favorite techniques are increasingly accurate and precise and some applications, like next-gen sequencing, will have you swimming in data analysis for weeks. That’s not such a […]
Top Five Reasons To Automate Your Epigenetic WorkflowAugust 3, 2011The word “automation” conjures up images of the future complete with robot butlers and flying cars, but the reality is that automation is here now, and it can change your everyday life in a big way. In the lab, automated instruments have already impacted how we use common techniques like PCR and sequencing. Today new […]
ENCODE and Roadmap Epigenomics Antibody Validation DatabaseJuly 19, 2011Many epigenetics techniques and projects rely on high-quality antibodies, but not all commercial antibodies perform well enough to get the job done. On top of that, there’s no uniform standard, or easy steps to fully validate a good antibody. With help of the Park lab at Harvard Medical School, there is now a place that […]
Methylome Analysis Today: No One is PerfectMay 18, 2011With everyone focused on their own daily grind, its easy to gloss over some of life’s more philosophical questions like: “Does a falling tree make a sound if no one is there to hear it?” “What is the sound of one hand clapping?” or even “Are my methylome studies really accurate?” In an Epigenomics review […]
RNA Immunoprecipitation Comes Of AgeMay 17, 2011RNA Immunoprecipitation (RIP) is growing up. After suffering through some awkward adolescent years, RIP has evolved from its humble beginnings in a few hardcore labs and is now stepping out shadow of its more famous cousin, Chromatin Immunoprecipitation (ChIP). The more mature RIP has been steadily building its fan base too with curious researchers seeking […]