eBook: Epigenetics of COVID-19September 22, 2022COVID-19 has been one of the biggest public health issues in recent history and has changed the daily lives of almost everyone on the planet. Many researchers, biotechnology and pharmaceutical companies have been working around the clock since the novel coronavirus outbreak started to try to develop new tools to test for and treat the […]
Now In Print! – New Technologies Leave their Mark on Imprinting Control RegionsJune 19, 2022Genomic imprinting typically lets our parents leave their mark on our genomes; however, new technological advances are now allowing us to leave our mark on imprinting! The first of our epigenetic exposés that went into print reports on how multiple modalities uncovered complex epigenetic crosstalk that regulates allele-specific gene expression at potential imprinting control regions […]
Dr. Steve Chan: The Epigenetic Regulation of Breast CancerJune 9, 2022Using unbiased ChIP-Rx analyses to discover a novel role for CTR9 in the epigenetic regulation of PRC2 subtype switching in breast cancer Our colleagues at Proteintech hosted a webinar from Dr. Steve Chan from The University of Wisconsin-Madison, who reviewed their recent paper “The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 […]
eBook: Epigenomics of SpermJune 9, 2022Some of the most interesting and important epigenetic phenomena occur in sperm. In addition to passing genetic paternal information, experiences and exposures can be encoded in the epigenome and inherited as well. In this EpiGenie ebook, we present summaries of several studies on exploring the role of epigenetic processes in sperm biology. They are divided […]
Webinar: Chromatin Immunoprecipitation (ChIP) Workshop – Dr. Toryn PoolmanFebruary 28, 2022If you’re new to chromatin immunoprecipitation (ChIP), or you’re thinking about giving it a try, you will want to take the time to watch this webinar first! Our friends at Proteintech put together an excellent workshop led by Dr. Toryn Poolman at University College London that covers a ton of tips and tricks that will […]
A Suite of New Tools to Solve Single-cell Epigenetic EnigmasDecember 23, 2021Welcome explorers of the epigenome! Are you looking for new tools to help answer the toughest of epigenetic enigmas? Then check out this suite of single-cell methods papers from technologically-talented teams led by Aviv Regev (Broad Institute of MIT and Harvard) and collaborators. inCITE into How Transcription Factors Shape In Vivo Gene Expression A collaboration […]
Epigenetics Takes the Wheel as the Brain Mapping Project Gets Motoring!October 30, 2021It’s easy to get lost when motoring down the epigenetic landscape; thankfully, a group of cunning cartographers from the Brain Research through Advancing Innovative Neurotechnologies Initiative Cell Census Network (or BICCN for short) has generated single-cell maps to guide your voyage of the brains’ motor cortex. Although this epigenetic road trip may be too long […]
An Oliver’s Twist on an Old Tale: Orphan CpGs Will Have You Asking for MoreJuly 17, 2021Move over Oliver Twist, there’s a new orphan in town to satisfy our hunger for stories of DNA methylation. Two new tales of orphan CpGs help them find a home in our hearts and epigenomes through the application of cutting-edge epigenomics techniques and genetic engineering to embryonic stem cells and neuronal cells. Making the Right Connections: […]
It’s Nature versus Nurture in an Epigenetic Rejuvenation Face-off!July 15, 2021The age-old battle of nature versus nurture has entered new frontiers with two exciting studies exploring different mechanisms that drive “epigenetic rejuvenation” – also known as the science of how our old and creaky DNA methylation-based epigenetic clocks can be wound back into a frolicking and fancy-free state. Together, these studies demonstrate the two faces […]
New Single-cell CRISPR Screens “ATAC” Chromatin AccessibilityJune 6, 2021Have you been struggling to agree on a plan of action for your recent epigenetic experiments? Have you been fighting over just what strategy to use to decipher how genetic alterations affect the epigenetic landscape? While we should all follow John and Yoko’s example and try to give peace a chance, you sometimes need to […]