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Features

EpiGenie Features call out new Methods, provide Insights into emerging trends, or sometimes just share technical tips from the experts in our community.

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NOMe-Seq Secrets Revealed

February 17, 2014

You’ve read the NOMe-seq (Nucleosome Occupancy and Methylome sequencing) papers. Seen the splashy advertisements. Now, we’ve consulted with the experts at Active Motif to get the inside scoop on how to get started, and get the most out of your NOMe-seq experience. NOMe-Seq was originally published and developed by researchers in the Peter Jones lab […]

Environmental Epigenetics Timeline

February 11, 2014

Thanks to growing interest from the general public, environmental epigenetics is a red-hot topic with no signs of cooling off anytime soon. We’ve certainly covered our fair share of research with an environmental slant to it, so if you want to review, research, or just plain get up to speed on the subject, these articles […]

Enhancers: A Review of the “Other” Regulatory Region Timeline

February 10, 2014

Promoters and UTRs seemed to have grabbed the better part of the limelight in recent years, but let’s not overlook enhancers. These mysterious pockets of regulatory potential are full of surprises. Read all about the epigenetic breakthroughs in the understanding of enhancers.

Epigenetics of Cancer Timeline

February 9, 2014

Epigenetic mechanisms have been studied in cancer for decades. Unfortunately, we haven’t been around that long, but check out these great articles that capture the recent history of epigenetic breakthroughs in cancer.

The Rise of lncRNAs Timeline

February 9, 2014

Long non-coding RNAs, also known as lncRNAs, are gaining a truck load of momentum in the field of the epigenetics. Here we highlight the hottest research, methods papers, and the occasional interview centered around these long and curvy regulatory RNAs.

Evolution of Advanced Sequencing Timeline

February 7, 2014

In a few short years. advanced sequencing has become nearly ubiquitous. Here we provide a history of how emerging sequencing technologies have driven epigenetic research and understanding.

Zymo-Spin™ ChIP Kits Give Chromatin Immunoprecipitations the Run-around

February 5, 2014

After an extensive development and beta-testing process, the innovators at Zymo Research have unveiled the new Zymo-Spin™ ChIP Kit, which provides a whole new twist to standard chromatin precipitations. Special Discount to EpiGenie Readers: Get 20% OFF and a free “Blame It On My Epigenetics” T-shirt with every purchase of Zymo-Spin™ ChIP Kit (Catalog No. […]

Three Dimensional Chromatin & DNA Replication with Dr. David Gilbert

February 3, 2014

Dr. David Gilbert discusses the ins and outs of 3-D chromosome folding, DNA replication and the highly dynamic cell nucleus. 3-D Chromatin and DNA Replication There’s no question. The thing that I’m most excited about is the uncanny alignment between three dimensional chromatin confirmation maps and replication timing. The alignment is the greatest alignment that […]

The New Players in Epigenetic Reprogramming with Dr. Wolf Reik

February 3, 2014

Dr. Wolf Reik discusses the latest advances in epigenetic reprogramming, and what those new discoveries might lead to. The New DNA Methylation Landscape So it’s become apparent in the last two years, I guess, that there is this process of genome-wide epigenetic reprogramming which occurs naturally in germ cells, early embryo stem cells, et cetera, […]

Webinar: Mechanisms of Epigenetic Regulation in Stem Cells and Development

January 31, 2014

Dr. Alexander Meissner discusses the roles of epigenetic mechanisms in stem cells and development. Cytosine methylation in mammals is an epigenetic modification that is largely restricted to CpG dinucleotides and serves multiple critical functions including stable repression of target promoters, maintaining genomic integrity, establishing parent-specific imprinting patterns, and silencing endogenous retrotransposon activity. In somatic tissues, […]

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