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Features

EpiGenie Features call out new Methods, provide Insights into emerging trends, or sometimes just share technical tips from the experts in our community.

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Get the Lead Out of Your Epigenome

October 1, 2013

What’s mainly orange, sometimes a little black, and usually obese? Congratulations if you guessed Agouti (Avy) mice! (And you may want to consider spending less time in a vivarium) These chubby little creatures are well established as environmental epigenetics models because a number of environmental exposures are known to alter DNA methylation at the Avy […]

Webinar: Epigenomics – One Molecule at a Time with Dr. Paul Soloway

September 16, 2013

Dr. Paul Soloway, PhD discusses his latest work on technologies that enable the interrogation of epigenetic marks on a single molecule. **this webinar is no longer available** Epigenomic analyses are used for many applications, including discovering gene regulatory mechanisms; characterizing non-genetic transmission modes of adaptive and disease traits; identifying and detecting disease biomarkers; and for […]

Mind Games: Sorting Out Brain Cell-type Specific Methylation

September 10, 2013

The human brain is the prime example of “highly specialized and diverse functions arising from the same genetic program.” But that comes at steep price. Our most complex organ is, well…very complex. Not only do it’s epigenetic marks constantly change both spatially and temporally but it’s also mainly and almost equally composed of two very […]

Priming Cancer Therapies with Epigenetics with Dr. Peter Jones

September 9, 2013

Dr. Peter Jones of the Norris Comprehensive Cancer Center at USC discusses the positive impact epigenetic therapies are having in the clinic. Priming Cancer Therapies with Epigenetics with Dr. Peter Jones Well, I think the thing that excites me the most is the increasing successes of epigenetic therapies in the clinic. And so I […]

Stem Cell Conference Highlights Timeline

September 4, 2013

Stem Cells are a hot topic these days. Here we provide a history of epigenetic breakthroughs in this interdisciplinary field as told through our Conference Coverage.

Genome-wide and Gene-specific Analysis of DNA Methylation

September 3, 2013

EpiGenie recently reviewed the text Epigenetics by Jorg Tost. Here is a more in depth summary of one the chapters provided courtesy of JA Gill who is a molecular biologist at NOAA in the Northwest Fisheries Science Center, to give you a little sneak peek into what the whole book is all about: Methods for […]

RRBS and 450k Arrays Face Off Over DNA Methylation Analysis

August 27, 2013

DNA methylation has been a cornerstone of epigenetics research from the start, and the emergence of technologies that make investigation of the modification more accessible has only made the DNA methylation field even hotter. Several tools and techniques are available to assess DNA methylation levels, but two in particular, reduced representation bisulfite sequencing (RRBS) and […]

Webinar: Life Long Changes in DNA Methylation & ncRNAs in Fetal Alcohol Syndrome (FAS)

August 22, 2013

Western University’s Ben Laufer (Ph.D. Candidate) discusses how bioinformatic software was used to establish that even moderate exposure to alcohol during pregnancy, equivalent to a few beers every now and then, can produce profound and heritable variations in development, behaviour, and learning that are maintained in the exposed fetus for a lifetime by altered epigenetic […]

MeCP2, Rett Syndrome and Getting to Know the Brain with Dr. Adrian Bird

August 6, 2013

Dr. Adrian Bird discusses what MeCP2 has to do with Rett Syndrome, and researchers still have a long way to go towards understanding the human brain. MeCP2, Rett Syndrome and Getting to Know the Brain with Dr. Adrian Bird I think the protein we work on, MeCP2, which recognizes methylated DNA, we knew it recognized […]

Epigenetics in Plants Timeline

July 29, 2013

Plants can be so much easier to deal with than people. That’s probably why so many epigenetics breakthroughs have emerged from plant research, rather than studies of actual human beings. Read more about how plant epigenetics has helped shape our larger understanding of the field.

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