Transcription Factor Networking Predicts Histone ModsSeptember 22, 2014Computational networking is all the rage, not only can it help you keep track of your friends and colleagues but it can also reveal a surprising amount of information behind the regulation of gene expression. Now a computationally cutting edge team from the University of Edinburgh have found out how to use transcription factor binding patterns […]
Environmental enrichment stimulates neural 5hmC dynamicsSeptember 17, 2014Judging from the luxurious lifestyles of the rich and famous, it would seem there’s no denying the wonders of an enriched environment. Even at an epigenetic scale, enhancing your environment properly and with a bit of personal restraint leads to improvements in the brain aplenty, including learning and memory. A team from Emory University characterized the […]
The IsomiR Comsos: Population and Gender DependanciesSeptember 17, 2014While microRNAs have been generally thought of as very homogenous little genomic modulators, some new studies are finding that there is actually an entire miRNA cosmos out there with slight variations that are relevant to gender and population differences in mammals. Over at Thomas Jefferson University, Isidore Rigoutsos and his colleagues have already seen some pretty […]
Rewiring Stem Cell Transcriptional CircuitrySeptember 12, 2014It seems all that was needed for human stem cells to maintain their pluripotent state, was just a little transcriptional rewiring. This cellular circuitry wasn’t handled by a master electrician though, but rather a group of Cambridge area researchers. A collaboration involving the Babraham Institute, Cambridge Stem Cell Institute and the European Bioinformatics Institute, led […]
Webinar: “Precision Mapping”- High Resolution Mapping using ChIP-exoSeptember 12, 2014“Precision Mapping” – High Resolution Mapping Using ChIP-exo Presented by: Bryce Alves Ph.D., Research Scientist at Active Motif Abstract: Transcriptional regulation is a complex mechanism that involves changes in epigenetic modifications, transcription factors and cofactors, and chromatin structure. Loss of controlled transcription is often found in various human diseases, such as what is seen in […]
