Charting Where Noncoding RNA Transcription Kicks OffSeptember 24, 2013While ‘Dark Matter’ is thought to constitute roughly 85% of the cosmos, our genomic dark matter (i.e. noncoding RNAs) makes up an even larger portion (~95%) of our genetic content. Leaving the vastness of outer space to astrophysicists, Dr. Bryan Venters and Dr. Franklin Pugh at Pennsylvania State University focused on creating a map of […]
Trinucleotide Repeat (TNR) Disease Cheat SheetSeptember 16, 2013Trinucleotide repeat (TNR) diseases are some of the latest disorders to be linked to epigenetic state. So Dr. Marguerite Evans-Galea and colleagues at the Murdoch Childrens Research Institute and The University of Melbourne, wrote up this review to act as a sort of cheat sheet for the mounting evidence of epigenetic mechanisms in TNR. This […]
Webinar: Epigenomics – One Molecule at a Time with Dr. Paul SolowaySeptember 16, 2013Dr. Paul Soloway, PhD discusses his latest work on technologies that enable the interrogation of epigenetic marks on a single molecule. **this webinar is no longer available** Epigenomic analyses are used for many applications, including discovering gene regulatory mechanisms; characterizing non-genetic transmission modes of adaptive and disease traits; identifying and detecting disease biomarkers; and for […]
Zymo ChIP DNA Clean & Concentrator™: A New Twist on Chromatin ImmunoprecipitationSeptember 10, 2013If you’re one of those researchers who has been avoiding ChIP experiments like the plague because of the aggravating low yields and poor quality ChIP DNA associated with traditional ChIP protocols, then it’s time to give the ChIP DNA Clean & Concentrator™ (ChIP DCC™) Kit from Zymo Research a whirl. The ChIP DCC™ is a […]
Mind Games: Sorting Out Brain Cell-type Specific MethylationSeptember 10, 2013The human brain is the prime example of “highly specialized and diverse functions arising from the same genetic program.” But that comes at steep price. Our most complex organ is, well…very complex. Not only do it’s epigenetic marks constantly change both spatially and temporally but it’s also mainly and almost equally composed of two very […]
