Vitamin C in Media Critical for ES Cell 5hmCJuly 24, 2013Whether its pop culture (like the ongoing royal baby mania) or cell culture, there’s no denying the enormous impact that ‘media’ has on our life. In fact, new evidence shows that a little Vitamin C in cell culture media can influence mouse embryonic stem (ES) cells, like typical pre-teens, to undergo a blastocyst-like identity crisis. […]
The Dynamic EpigenomeJuly 24, 2013EpiGenie recently reviewed the text Epigenetics by Jorg Tost. Here is a more in depth summary of one the chapters provided courtesy of JA Gill who is molecular biologist at NOAA in the Northwest Fisheries Science Center, to give you a little sneak peek into what the whole book is all about: The Dynamic Epigenome: […]
Placental miRNAs Predict Infant BehaviorJuly 18, 2013Many parents consider their children’s behavior to be a bit of a mystery, (just ask anyone who has shared a plane ride with an unruly toddler) but new miRNA research hints that it may soon be possible to predict your child’s behavioral traits by a simple non-invasive test right after birth. A fortune telling team […]
EpiGenie Guide: RNA Immunoprecipitation (RIP) and BeyondJuly 10, 2013RNA binding proteins (RBPs) play important roles in many cellular and disease processes, together with their DNA binding brethren, they compromise almost one quarter of annotated human genes. The tools used to understand when and where these proteins bind and interact with RNAs in the cell have lagged behind those for protein-DNA interactions, although they […]
Disrupting DMNT1’s Cancerous InteractionsJuly 9, 2013It seems like almost every gene examined today has it roots in cancer, and epigenetic mechanisms haven’t missed the invite to that party. But with all these players comes an overwhelming heterogeneity that has troubled researchers looking for a cure ever since cancer was described as an epigenetic disease. Some research groups have tried out […]
