State of Methylome Analysis: Genome-Wide Methylation Techniques ReviewFebruary 11, 2010The State of the Union Address and the drama/commentaries that accompany it have come come and gone, but a fresh Nature Review produced by USC’s Peter Laird now provides the epigenetics community with a State of Methylome Analysis. For the epigenetics researcher, it is every bit as insightful but won’t take as much time to […]
Histone Mods Choose Alternative Splicing LifestyleFebruary 8, 2010We can’t say we were surprised to hear that histone mods lead an alternative lifestyle—not that there’s anything wrong with that. It’s been theoretically shown that nucleosomes and their histone marks are involved in splicing by crunching data from previous experiments. Now, scientists at NCI, the University of Toronto, and the University of Texas Health […]
Methylome Stays Fashionable Throughout DifferentiationFebruary 5, 2010Our fashion sense evolves as we do. Just as you may trade your flip-flops for a business suit as you climb the corporate ladder, DNA methylation changes its style in cells that become more committed. To size up these methylation changes during differentiation, researchers at the UCSD Department of Reproductive Medicine and GIS in Singapore […]
Self Service Transcription Lane Now Open for miRNAsFebruary 2, 2010Many retailers have opened up self-service checkout lanes lately, which are great for those customers with just a few items, or don’t want to get stuck behind the old couple who still pays with paper checks. According to a recent report, when it comes to transcription, at least some miRNAs might have the option to […]
In Evolution, Change Is the Only (Epigenetic) ConstantFebruary 1, 2010Most of us are thrown for a loop when conditions suddenly change, but some are better able to cope than others (we still haven’t gotten used to the new Facebook format). A recent PNAS paper by Johns Hopkins’ epi-gurus Andrew Feinberg and Rafael Irizarry makes the case that some of this adaptability stems from stochastic […]
