Ta-da! Blood Cells Transform into iPSCsJanuary 20, 2011Turning a cell into an induced pluripotent stem cell (iPSC) is tricky. It turns out that blood cells have an edge—they already epigenetically resemble iPSCs. When U.S. and Chinese researchers poked around the DNA of human CD34+ cells from umbilical cord blood and adult blood, they found that the promoters’ methylation patterns looked a heck […]
KDM6B: H3K27me3 Demethylase Gone BadJanuary 19, 2011KDM6B is just your average histone demethylase that usually goes about its business stripping methyl marks from H3K27me3 without any drama. That is, until it gets a little out of control and starts demethylating genes associated with Hodgkin’s Lymphoma (HL). Scientists at the University of Birmingham, UK were looking into the role of H3K27 demethylation […]
Stem Cells Can’t Hold Their LiquorJanuary 17, 2011Growing up, you always hear that drinking alcohol kills brain cells. According to a new report (not to mention a slow recovery from the EpiGenie New Year’s Eve Bash) there’s definitely some truth to that old adage. Researchers at Indiana University looked at alcohol’s effect on neural stem cells (NSCs) during development by running NSC […]
Top Epigenetics Technology Features on EpiGenieJanuary 14, 2011Want to catch up on some of the latest methods, new technologies, and expert technical tricks? You’re in the right place. Here’s a list of our favorite emerging Technology and Methods articles from the last year or so to really jump-start your 2011. Check ‘em out! DNA Methylation Analysis Methylome Analysis Snapshot February 11, 2010. […]
Chromatin: 2010 2nd Half Editor’s FavoritesJanuary 6, 2011Chromatin research keeps blowing up right along with the rest of the epigenetics field over the last six months or so of 2010. Here are some of our favorite Chromatin headlines covering things like chromatin remodeling, transcription ehancers, histone turnover and nucleosome positioning. Chromatin Remodeling The dynamics of nucleosome interactions and displacement during cellular processes […]
