Decitabine Scores a Cancer Therapy ‘Hat Trick’January 7, 2014The cancer treatment field scored a nice win to kick off 2014. Past studies have hinted that epigenome modifying drugs show great potential in the clinic, but new findings from Kunle Odunsi and team at the Roswell Park Cancer Institute in Buffalo, New York has demonstrated that a combinatorial approach using Decitabine (a DNA ‘demethylater’) and […]
Chromatin Interaction Analysis is All About TimingJanuary 3, 2014Formaldehyde treatment is a popular way to cross-link proteins and DNA during Chromatin Immunoprecipitation (ChIP), an assay that has been widely used to characterize protein-DNA interactions. Now, a team from University of Virginia Health System has enhanced this time-tested formaldehyde fixation approach to understand how fast/slow proteins bind to DNA and the stability of chromatin […]
Epigenetic Technology: 2013 Editor’s FavoritesDecember 18, 2013In 2013, technology impacted nearly every facet of our lives: from improving Instagram selfies, to squeezing even more knowledge from epigenetics research. Check out some of our favorite Technology features from the past year: Genome Editing We love the potential of Genome Editing. Led by methods like CRISPR-Cas, this emerging field has really boomed this […]
Epigenetics 101: You Can’t Always Blame Your Parents with Alberto PerezDecember 17, 2013EpiGenie reader Dr. Albert Perez lays out some of the basic concepts behind epigenetics, and explains how being a red-head in Spain started him on a path to explore DNA and the epigenome.
DNA Methylation and Diet: You Are Also What Your Father AteDecember 17, 2013Freud famously blamed mothers for nearly everything, and when early epigenetic studies indicated that you are what your mom (and grandma and great-grandma) ate, it seemed to back him up. But when it comes to complex traits and environment, a new report from scientists at McGill University (Montreal) found that a father’s diet shapes a child too. […]
