How Fatty Acids Alter the EpigenomeJune 22, 2014It’s is easy to blame our parents and their epigenetics whenever we’re struggling to squeeze into our summer swimwear, but a brand new study illustrates how our own dietary choices have a big impact on health. A team from Lund University have shown just how eating fatty acids is not only bad for your waistline, […]
Webinar: The Good, the Bad and the Ugly: Getting Reliable ChIP Data From Difficult SamplesJune 19, 2014Johanna Samuelsson Ph.D., Senior Research Scientist at Active Motif covers some techniques to get killer data, even when your samples don’t make it easy. ChIP Overview I’m going to talk about chromatin immunoprecipitation, not necessarily focusing on all the specific details, but more the challenges with the technique, and those tricky samples that many of […]
Wild-Type Inheritance of DNA MethylationJune 12, 2014It seems like all news lately is focused on the terrors of the world and transgenerational epigenetic inheritance has been no exception, usually with a strong focus on how an exposure or trauma finds a way to haunt generations. But now now an optimistic team from UCLA have shown that a lot can be learned from examining […]
Mechanosensitive DNA Methylation Keeps the Flow GoingJune 12, 2014Going with the flow is a sound strategy unless, of course, something is disturbing that flow. Researchers from the Georgia Institute of Technology and Emory University have shown that when blood flow is disturbed (d-flow) there is a responsive stream of gene expression changes triggered by mechanosensitive DNA methylation. Lead author Jessilyn Dunn shares that “It was […]
ChIP Shows Cas9 Can Miss the MarkJune 10, 2014Staying on target has always been the CRISPR/Cas9 claim to genome editing fame, leading to incredible breakthroughs in the application of this bacterial immune system to mammals and as a cure for inherited disease. But now a sharpshooting team from the University of Virginia have used a clever application of ChIP-Seq to show that sometimes Cas9 can cause off-target effects. […]
