DNA Methylation Runs the Genomic DefenseSeptember 12, 2012Novel research findings over the last last five years have introduced more exceptions than rules in the field of DNA methylation in gene silencing. Whether DNA methylation stars as the cause or effect in the thickening regulatory plot continues to be discussed in labs around the world. A British team of researchers led by Dr. […]
EpiGenie Reviews Non-Coding RNAs and Epigenetic Regulation of Gene ExpressionSeptember 11, 2012In recent years, studies exploring the modulation of gene transcription by non-coding RNAs have definitely been on the rise. This book, Non-Coding RNAs and Epigenetic Regulation of Gene Expression, written by a selection of highly regarded scientists, and edited by Kevin Morris, represents an overview and summary of this important new field to date. It’s […]
Predicting Gene Expression with Chromatin FeaturesSeptember 11, 2012As any weather forecaster can tell you, making accurate predictions is tough. But researchers now report that they’ve confirmed the power of chromatin features to predict gene expression. They’ve also come up with some new insights, too. Sure, some histone mods are associated with transcriptional repression, whereas others typically mark active spots. But many studies […]
Promoters Reach Out to Far -Away ElementsSeptember 11, 2012Now that the Olympic games are over, researchers in the ENCODE consortium have announced that they’ve just finished another Olympic effort of their own—the large-scale mapping of functional elements in the human genome. And just like the flexible “Fierce Five” U.S. women’s gymnastics team, it turns out that the genome is very bendy, looping around […]
Prediction Models Re-Write the Book on Nucleosome Occupancy and miRNA TargetingAugust 23, 2012A pair of newly released papers prove that you don’t always have to run more wet lab experiments to learn something new, you just need to look the data in a different way. The two research groups both used simulations and prediction algorithms, like the ones found on our Epigenetics Databases and Tools list, to […]
