RNA Pol II Calls the Shots in Random Monoallelic ExpressionAugust 15, 2011Just because two things ultimately do the same thing doesnât mean theyâre equivalent. Take Facebook and MySpace, for example. Researchers from the University of Washington say that imprinting and random allele-specific expression have two very different mechanisms, even though the outcomeâonly one of the two alleles of a gene is translatedâis the same. H3K9me3 and […]
Microfluidic qRT-PCR Unlocks Single Cell miRNA SecretsAugust 12, 2011Recent headlines tell us that the average American lives in a household of 2.62 people, chows down too many potato chips, and thinks that the âDirty Dancingâ remake is a bad idea. But averaging over populations obscures the often highly variable characteristics of individuals, and the same is true for cells. To get a better […]
EpiGenie Stem Cell Epigenetics ReviewAugust 4, 2011Weâre big fans of stem cell research, the vast potential it represents and the close connection it has to epigenetics. Apparently we arenât alone either, judging by the avalanche of top-notch papers that regularly cross our monitors. Weâve even give serious consideration to launching another site just to be able cover the area properly (StemGenie, […]
A Beginner’s Guide to ChIPAugust 3, 2011Do you lay awake at night reflecting on how much you want to get started with ChIP, but stressed that you donât know where to start? Who doesnât? Good thing for you, our friends at Abcam have come to your rescue, so you can rest at ease counting sheep instead. Abcam just published a killer […]
Targeting Brd4 Fends Off Acute Myeloid LeukemiaAugust 3, 2011Chromatin mods should be good drug targets for cancer therapies, but sort of like Facebookâs privacy policy, cancer epigenetics is so complex that no one completely understands all the nuances. So instead of spending time on the usual epigenetic suspects, researchers at Cold Spring Harbor in New York kept an open mind and performed an […]
