DNMT1 the Key to Radiant Skin?January 20, 2010The key to younger looking skin isn’t in expensive nip/tuck work or clay masks, but as a recent Nature paper shows, it’s actually DNMT1 that plays a major role. Thanks to DNMT1, whenever you shed dry skin, it is continually replaced with a new layer. That’s right—the same DNA methyltransferase that plays a role in […]
Epstein-Barr Virus is Crafty with DNA Methylation in LatencyJanuary 20, 2010The 80s TV show MacGyver featured a main character who was always able to get himself out of dangerous situations with just his wits and clever use of whatever materials happened to be lying around. In much the same way, EBV has figured out how to harness a host B cell’s DNAm machinery to modulate […]
More DNAm Data, Less Sample: Reduced Representation is No BSJanuary 13, 2010When someone tells you that they can save you time, money and sample, the magic trifecta for most scientists, your first thought is probably: “Bull&@%!”…your second thought might be: “Where do I sign up?” A new Nature Methods article from researchers at Broad, MIT, Harvard, and the Max Planck Institute promises to do just that […]
Two ES Cell Types Find Some Common GroundJanuary 6, 2010Coming from different backgrounds doesn’t make it impossible to find common ground. Just look at nuclear transfer-derived ES (ntES) and in vitro fertilized embryo-derived ES (IVFES) cells. Sure, they’re from different sides of the ES cell tracks, but as researchers from Michigan State University found out, once they’ve differentiated it hardly seems to matter. NtES […]
Zygotes Reboot On Paternal Methylation PatternsJanuary 6, 2010Kids often rebel against their parents as they grow up, and as it turns out, so do zygotes. Feeling “too cool” for their paternal sperm’s methylation patterns, zygotes assert their individuality by “rebooting” the inherited 5mCs and starting from scratch. But up until now, it was their little secret how they pulled it off. Researchers […]
