The State of Epigenetic EditingSeptember 27, 2012If the field of epigenetics is heading into adolescence (rapid growth, disruptive, with occasional data tantrums), the arena of Epigenetic Editing (gene-specific rewriting of epigenetic marks) is more zygotic than anything, with far more questions than answers. But the concept of systematically manipulating epigenetic marks to modulate gene expression is injecting some air back into […]
Free White Paper: Histone Acetylation and Methylation – Epigenetic Modulators of Gene ExpressionSeptember 26, 2012Histone acetylation and methylation are important cellular processes, but it can be hard keeping track of the structural ups and downs from HATs and HDACs. This free white-paper provides an informative, concise review of the key players in histone acetylation and methylation and their impact on specific residues. Download here >>>
RNA Methylation Adds Some Stability to a Chaotic CellSeptember 26, 2012We could all use a little more stability in our lives, and now researchers in Germany say that tRNAs get more stable when they are methylated on specific cytosines. This stability helps ensure that cells keep making proteins for proper development and differentiation. The role of cytosine-C5 methylation on tRNAs has been more mysterious than […]
NOMe-seq Goes Genome WideSeptember 19, 2012NOME-seq (Nucleosome Occupancy and Methylome Sequencing) made a big splash when it was introduced just over a year ago because of its novel ability to profile nucleosome positions and DNA methylation at the same time, on a single DNA strand. Now researchers from the University of Southern California Epigenome Center have powered-up the technique by […]
From A to G: The Ins and Outs of ChIP BeadsSeptember 12, 2012If you don’t run chromatin immunoprecipitation (ChIP) experiments on a daily basis, there’s a good chance that you find the dizzying variety of available immunoprecipitation bead choices a little overwhelming. We asked the ChIP experts from EMD Millipore to help us break down what you need to know about ChIP beads so that you choose […]
