Elevate Your Epigenetics Game with DeepBlue and epiGbsMarch 2, 2016When it comes time to tackle the big data of the epigenome, tools and databases are your best friend. However, in today’s modern world, there’s more than one way to crack the epigenome and now two new tools serve up some interesting perspectives on the use of reference sequence. Going Deep into Databases Felipe Albrecht […]
Aspirin and lncRNA Team Up on TumorsMarch 1, 2016Over 100 years ago, the founder of chemotherapy, Paul Ehrlich, coined the term “magic bullet” to describe an ideal therapeutic agent used to target disease, such as cancer. Since then, we have assessed many different anti-tumorigenic compounds, although we are only beginning to understand just how some of these bullets hit their target. This understanding, […]
MeRIP-seq, N1-methyladenosine (m1A), and the Expanding EpitranscriptomeFebruary 23, 2016There’s no denying that understanding a new language can be tricky. Without a complete alphabet, the most important messages can be lost in translation. When it comes to complex languages, the epigenome is no exception. There are a number of RNA base modifications involved in post transcriptional regulation, including pseudouridine (Ψ) and 5hmC, and there’s […]
Towards Blood DNA Methylation as a Pan-Cancer Surveillance ScreenFebruary 5, 2016Early and less tedious cancer diagnosis can prevent future complications and improve patient outcome, however past studies have revealed that the markers of most cancers are as unique as snowflakes. An enticing solution for this heterogeneity would be to screen for any type of cancer using one detection system to ‘rule them all’. Differential DNA […]
DNA Methylation and Transcription Data from Single Stem CellsJanuary 28, 2016Ever wanted to be able to do two things at the same time? Like work and have a social life? Eat pizza and still fit in your new purchases? Pat your head and rub your belly? While these highly important combinations remain almost impossible (at least for the EpiGenie staff), a stellar cast of scientists […]
