Blame Your Old Man: Age-Related Sperm Methylation Changes May Up Disease OddsJuly 24, 2014Delayed parenthood in developed countries means more old dads. Who cares you ask? You should, as this trend doesn’t just increase early morning traffic at Starbucks, it can also increase the incidence of autism, bipolar disorders, schizophrenia, some forms of cancer, or other disorders that accompany the offspring of older fathers. Way to go Dad; […]
Webinar – Bringing ChIP Seq Data into Focus: Advanced Normalization StrategiesJuly 23, 2014If you’ve ever struggled to make sense of your ChIP Seq data, then check out this webinar presented by our colleagues at Active Motif, to get some ideas on how to bring some order to the chaos of ChIP-seq. Presented by Brian Egan, Ph.D, Epigenetic Services Manager at Active Motif Normalization of ChIP-seq Data Today, […]
Fetal Undernourishment Creates Temporary Transgenerational EffectJuly 11, 2014Transgenerational epigenetic inheritance is one hot topic, and it has long been shrouded in skepticism, but a number of cases and mechanistic insights into transgenerational epigenetic inheritance have helped molecular biology move past the limits of genetic determinism. Now a team from the University of Cambridge show that fetal nourishment results in a transgenerational epigenetic effect, rather than true […]
Reaction Biology Scores NIH Grant for Epigenetic Drug DatabaseJuly 11, 2014Epigenetic databases are one of of our favorite futuristic tools and now a time traveling crew from Reaction Biology Corporation (RBC) land a grant from the National Center for Advancing Translational Sciences (NCATS) to create an impressive database of epigenetic drug interactions. The team at RBC is undertaking a colossal effort examining a library of 1,400 compounds, including almost every FDA approved drug. […]
Cesarean Alters DNA Methylation in Infant Blood Stem CellsJuly 9, 2014There’s no denying that the process of giving birth is an unforgettable experience for those involved but now it seems the labor of love could also be important for programming an infants development. Researchers from the Karolinska Institutet (Sweden) drop some knowledge about the mechanosensitive nature of DNA methylation and show that birth via Caesarean Section (CS) […]