The Epigenetics of Organ TransplantationJanuary 31, 2013Dr. Daniel Salomon discusses the state of organ transplants, what obstacles exist, and how epigenetics might be central to improving long-term health in patients. The Challenges in Transplantation My background is in transplantation medicine, transplantation immunology. And my interests are to change the way we manage patients. There’s a huge series of challenges right […]
MBD-SNP Analysis Shows that Prostate Cancer is PersonalJanuary 28, 2013These days, everyone wants to stand out. Just look at Lady Gaga and Nicki Minaj—in fact, you can’t not look at them. It turns out that metastatic prostate cancer tumors also stand out from patient to patient, as long as you know where to look. A team of Johns Hopkins researchers used methyl-binding enrichment and […]
DNA Methylation Map Based on Data from 82 Human Cell Lines and TissuesJanuary 21, 2013Christmas has come and gone, but the ENCODE Project is the gift that keeps on giving. Using samples and data from ENCODE (in combo with their own data), researchers have come up with a single-base resolution map of DNA methylation across 82 human cell lines and tissues, including many cancers. With the ever increasing DNA methylation data […]
MeCP2 Puts 5hmC in a Bind in Active Neuronal GenesJanuary 7, 2013A good actor can play very different roles and still make you believe in the character. For example, who knew Wolverine could emote and sing, like Hugh Jackman does in Les Misérables? Just the same, it turns out that MeCP2, a protein thought to repress transcription by binding to 5mC (5-methylcytosine, actually seems to encourage […]
Top Epigenetics & ncRNA Conference Picks for Winter 2013December 27, 2012We’re on the verge of 2013. For those of you who want to up your epigenetics research game and have some fun in the process, we’ve got conferences you should definitely check out. The year starts off a little quiet on the numbers front, but the quality more than makes up for it. January […]