Ontario Cancer Institute Epigenetic Research PositionsJune 17, 2012News reports tell us how tough the job market is lately, so we’re doing our part for the global economy by posting these two new epigenetic research positions that the Ontario Cancer Institute (OCI) is looking to fill. Who knows? Maybe one of them is perfect for you. Postdoctoral Research Fellow or Research Associates – […]
Webinar: Chromatin Immunoprecipitation (ChIP) Struggles and SolutionsJune 15, 2012If you’re new to chromatin immunoprecipitation (ChIP), or just want to brush up on your skills, this webinar might be a good place to start. Chromatin Immunoprecipitation (ChIP) Struggles and Solutions Presented by: Eric Neely, Ph.D Senior Scientist at Novus Biologicals View Webinar >>
Abcam EpiSeeker Assays Lead the Search for DNMT KnowledgeJune 13, 2012DNA methyltransferases (DNMTs) have been a trending topic in the epigenetics community for years because of their role in cytosine methylation. Studies that set out to pin down the precise function of DNMTs in various disease and developmental states often introduce more questions than answers. To get to the bottom of DNMT function, you need […]
DNA Methylation Addiction Keeps Cancer Cells AliveJune 13, 2012Addictions are so strong that some people think they can’t live without them. For cancer cells, that’s actually the case. Cancer cells’ DNA methylation addiction actually keeps them alive, according to a group of California researchers. Altered DNA methylation is just one of many changes that go down when a cell becomes cancerous. The researchers […]
EZH2, PRC2 Get a Little Guidance From Intronic RNAs to Find Target GenesJune 7, 2012When touring an unfamiliar city or museum, it often helps to have a good guide if you want to see the best sights. Researchers in Spain now report that intronic RNAs, like a well trained herding dog, usher the repressive polycomb complex right to the specific chromatin regions they need to target in order to […]
Epigenetics Book Reviews and Chapter SummariesJune 6, 2012Over the last year EpiGenie has reviewed a couple of the latest epigenetics textbooks for the site. As good citizens of the earth, we of course looked for ways to recycle the books (and the knowledge inside of them) once our writers were done with them. So, we sent our copies out to readers and […]
Covaris AFA: Shear Elegance for ChromatinJune 5, 2012Chromatin shearing is a key step in the ChIP workflow that can dramatically impact your experimental outcome, but so often the task of chromatin shearing is tackled with just brute force. Sub-optimal sonication or enzymatic approaches are like using a sledgehammer to chop fruits and vegetables. Fortunately, Covaris’ Focused-ultrasonicators use Adaptive Focused Acoustics (AFA) technology […]
Webinar: Defining Chromatin State by Characterization of Chromatin RegulatorsJune 4, 2012EMD Millipore sponsored this recent webinar last month, that you can now replay at your convenience. Check it out. Chromatin Regulators (CRs) control chromatin structure, yet the rules governing these processes remain obscure. This presentation details a systematic approach to infer the function of CRs by mapping genome-wide CR-binding, and presents a novel approach for […]
Nature AND Nurture Both Contribute to DNA MethylationJune 1, 2012A recent pub led by a talented research team might call for a ceasefire in the old “nature vs. nurture” argument. Researchers in The Netherlands and the U.S. say their new study on people conceived or born during the Dutch Famine of 1944-1945 piles on even more evidence that the prenatal environment and your genes […]
For Histone Variants It’s All in the NameMay 31, 2012Understanding the nomenclature for histone variants can sometimes be like deciphering an ancient language without a translation app. And as more variants are discovered without a naming convention to guide the process, the confusion just keeps growing. That’s why Steve Henikoff and the rest of the attendees of the EMBO Workshop on Histone Variants last […]