DNMTs Determine Radiation Sensitivity of Cancer Stem CellsJune 27, 2012Radiation therapy usually works well against cancer, but some cells that survive the blast can divide and become unstable (cancerous) much later on, causing a relapse. Researchers initially thought that DNA hypomethylation was to blame for “delayed radiation-induced genomic instability,” but a new study in Epigenetics, August 2012 shows that, at least for embryonic stem […]
EMD Millipore AbSurance™ Histone Peptide Arrays: Insurance for Your AntibodiesJune 23, 2012It’s never a bad idea to insure the important things in life against disaster. Wouldn’t it be great if epigenetics researchers could do the same for an upcoming experiment? Although they aren’t exactly in the insurance game, EMD Millipore has designed the new AbSurance™ Histone Antibody Specificity Arrays to act as a protective policy against […]
NIH Roadmap Epigenomics Program Data ResourceJune 18, 2012Last August, we shared with you some of the great new online resources being developed by the NIH Roadmap Epigenomics Program. Now, the latest issue of Epigenomics, has published an update of all the latest editions, tweaks and refinements they’ve made over the last year. The NIH Roadmap Reference Epigenome Mapping Consortium has created a […]
Exosome miRNAs Tell Liver Damage DetailsJune 18, 2012Sometimes many paths can lead to the same destination, and in the case of liver disease, it’s important for proper treatment to know the exact route that led to problems. New research shows that exosome miRNAs can tell scientists exactly how liver damage was caused. Several things, from chemicals to viruses, can trigger liver damage […]
Ontario Cancer Institute Epigenetic Research PositionsJune 17, 2012News reports tell us how tough the job market is lately, so we’re doing our part for the global economy by posting these two new epigenetic research positions that the Ontario Cancer Institute (OCI) is looking to fill. Who knows? Maybe one of them is perfect for you. Postdoctoral Research Fellow or Research Associates – […]
Webinar: Chromatin Immunoprecipitation (ChIP) Struggles and SolutionsJune 15, 2012If you’re new to chromatin immunoprecipitation (ChIP), or just want to brush up on your skills, this webinar might be a good place to start. Chromatin Immunoprecipitation (ChIP) Struggles and Solutions Presented by: Eric Neely, Ph.D Senior Scientist at Novus Biologicals View Webinar >>
Abcam EpiSeeker Assays Lead the Search for DNMT KnowledgeJune 13, 2012DNA methyltransferases (DNMTs) have been a trending topic in the epigenetics community for years because of their role in cytosine methylation. Studies that set out to pin down the precise function of DNMTs in various disease and developmental states often introduce more questions than answers. To get to the bottom of DNMT function, you need […]
DNA Methylation Addiction Keeps Cancer Cells AliveJune 13, 2012Addictions are so strong that some people think they can’t live without them. For cancer cells, that’s actually the case. Cancer cells’ DNA methylation addiction actually keeps them alive, according to a group of California researchers. Altered DNA methylation is just one of many changes that go down when a cell becomes cancerous. The researchers […]
EZH2, PRC2 Get a Little Guidance From Intronic RNAs to Find Target GenesJune 7, 2012When touring an unfamiliar city or museum, it often helps to have a good guide if you want to see the best sights. Researchers in Spain now report that intronic RNAs, like a well trained herding dog, usher the repressive polycomb complex right to the specific chromatin regions they need to target in order to […]
Epigenetics Book Reviews and Chapter SummariesJune 6, 2012Over the last year EpiGenie has reviewed a couple of the latest epigenetics textbooks for the site. As good citizens of the earth, we of course looked for ways to recycle the books (and the knowledge inside of them) once our writers were done with them. So, we sent our copies out to readers and […]