Headlines Archives - EpiGenie | Epigenetics, Stem Cell, and Synthetic Biology News

Headlines

Ever get that feeling that you forgot something? Well maybe you did, but it doesn't have to be recent epigenetics research if you scope out our Headlines each week.

Search Articles

Are Human Cord Blood iPSCs the Next Top Model?

July 23, 2014

It’s hard for most of us to imagine what life would be like without speaking, walking, breathing, and swallowing, but individuals suffering from motor neuron disease don’t have to imagine this scenario. Motor neuron diseases, like amyotrophic lateral sclerosis (ALS) (Lou Gehrig’s disease) and spinal muscular atrophy (SMA), strip thousands of people every year of […]

5′ UTR miRNA Targeting

July 21, 2014

The nightly news lately makes it seem like the world has gone upside down, and now we’ve got some science to back it. Honglei Zhou and Isidore Rigoutsos from Thomas Jefferson University recently revealed that mammalian miRNA targeting doesn’t always limit itself to 3′ miRNA action. It now seems that in addition to the traditional 3’UTR […]

Grab an Epigenetics Position at Active Motif

July 21, 2014

Our colleagues at Active Motif are searching for a new member for their team in the position of Product Specialist – Europe. If you dig epigenetics, and think you’ve got some business and marketing skills to go with it, then this may be a great fit for you! The crew at Active Motif is great […]

Chromatin Packaging in Embryonic Stem Cells and Sperm

July 16, 2014

Fitting all that chromatin into a tiny package is no easy ordeal, especially when pristine nuclear architecture is so crucial to things like cancer prevention. In order to learn more about the chromatin packaging of mouse embryonic stem cells (ESCs) and sperm, a team from the University of Massachusetts Medical School laid out some high-resolution nucleosome and transcription factor […]

Fetal Undernourishment Creates Temporary Transgenerational Effect

July 11, 2014

Transgenerational epigenetic inheritance is one hot topic, and it has long been shrouded in skepticism, but a number of cases and mechanistic insights into transgenerational epigenetic inheritance have helped molecular biology move past the limits of genetic determinism. Now a team from the University of Cambridge show that fetal nourishment results in a transgenerational epigenetic effect, rather than true […]

Reaction Biology Scores NIH Grant for Epigenetic Drug Database

July 11, 2014

Epigenetic databases are one of of our favorite futuristic tools and now a time traveling crew from Reaction Biology Corporation (RBC) land a grant from the National Center for Advancing Translational Sciences (NCATS) to create an impressive database of epigenetic drug interactions. The team at RBC is undertaking a colossal effort examining a library of 1,400 compounds, including almost every FDA approved drug. […]

Cesarean Alters DNA Methylation in Infant Blood Stem Cells

July 9, 2014

There’s no denying that the process of giving birth is an unforgettable experience for those involved but now it seems the labor of love could also be important for programming an infants development. Researchers from the Karolinska Institutet (Sweden) drop some knowledge about the mechanosensitive nature of DNA methylation and show that birth via Caesarean Section (CS) […]

Keeping Up with the TET Enzyme Family and DNA Demethylation

July 9, 2014

That wacky TET enzyme family is at again, but rather than being caught in some compromising positions with DNA or cheating on Cytosine; this time our favorite enzyme family is slacking off, or as they call it ‘working smart’ and splitting up important active DNA demethylation work. Researchers at the Mayo Clinic provide novel insight into how the TET […]

Targeted Chromatin Capture (T2C)

July 7, 2014

With great resolution comes great price and manpower requirements, so the demand for a happy medium has remained at large for all those trying to catch some chromatin conformation. New players like Capture-C have stepped up to the plate and now Researchers from the Erasmus University Medical Center (The Netherlands) announce T2C: Targeted Chromatin Capture. Chromosome conformation capture […]

Placental Biomarker Captures Maternal Stress

June 30, 2014

Stress has a funny way of sneaking up on you, and with the newly understood dangers of stress being transmitted across generations, keeping the drama to a minimum is huge concern for expecting mothers. So, wouldn’t it be nice to have some sort of an early stress warning device? Placental miRNAs have already been used to […]