Headlines Archives - EpiGenie | Epigenetics, Stem Cell, and Synthetic Biology News

Headlines

Ever get that feeling that you forgot something? Well maybe you did, but it doesn't have to be recent epigenetics research if you scope out our Headlines each week.

Search Articles

Chromatrap®’s FFPE ChIP Kits Unlock Your Sample Vault

July 18, 2016

If you’re like many of the researchers we’ve met over the years, you’ve been hoarding some of your favorite Formalin Fixed Paraffin Embedded (FFPE) samples deep in the recesses of a nondescript lab freezer, just waiting to be investigated. We get it; traditionally FFPE samples have been successfully used to analyze RNA and DNA, but […]

Top Upcoming Epigenetics Conferences

July 14, 2016

In today’s omic world databases are crucial, which is why always we keep our conference-ome up to date. Here’s a taste of what 2016 has left to offer for your next educational epigenetic excursion. EMBL’s Transcription and Chromatin (Heidelberg, Germany – Aug 27-30) Interested in transcription? Then this is the conference for you! This meeting […]

Top Upcoming Stem Cell Conferences

July 13, 2016

Conferences are ideal places to hear insights from the leaders in your field, to watch the up-and-comers present their new and exciting visions, and to network with potential collaborators (i.e., drink and eat and have some fun!). To assist you with these endeavors, EpiGenie brings you the pick of the bunch: some of the most interesting stem […]

scAba-seq: Single-Cell, Genome-Wide, and Strand-Specific 5hmC Sequencing

July 6, 2016

Usually, you don’t want your genome sequencing served up with a sugar coating; however, thanks to a clever a new 5hmC sequencing technique, we can indulge in some sweet single-cell and strand-specific insight. The study of 5hmC (5-Hydroxymethylcytosine) prevalence in DNA typically involves utilizing modified bisulfite sequencing, 5hmC specific antibodies, or restriction enzymes. Aba-seq makes […]

Epigenetic Assays Get Clinical: Comparison of DNA Methylation Assays and More

June 27, 2016

Four new papers co-published by an international consortium demonstrate and further the clinical potential of epigenetic assays. The series of manuscripts was led by Christoph Bock (CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences) and Stephan Beck (University College London). Comparison of DNA Methylation Assays Suited for the Clinic While there […]

Evolution Uses Bivalent Chromatin to Control Mammalian Development

June 22, 2016

A big event always requires a bit of prior preparation, and for evolution, mammalian development is no exception. The mammalian body plans have undergone massive evolutionary rearrangements and diversifications requiring the evolution of complex gene expression profiles. Recent studies in specific tissues in mammalian species have now linked these expression changes to the evolution of […]

Synthesizing A Human Genome

June 16, 2016

One score and six years ago, humanity embarked upon the Human Genome Project (HGP), sequencing all 3 gigabases of our genetic instruction manual. More than 1000 human genomes later, a consortium of synthetic biology heavy-hitters has proposed a new grand challenge. Appending “-Read” to the first project, they now propose Human Genome Project-Write, a quest […]

Watch out Cas9: Cpf1 Hits the Mark in Human Cells and Creates a Mouse Model

June 15, 2016

In the Wild West of CRISPR genome editing, Cas9 has established itself as a wrangler of animal models that takes out any sequence with an sgRNA bounty on its head. But now there’s a new sheriff in town with marksman aim. CRISPR from Prevotella and Francisella 1 (Cpf1) was brought forth by the pioneering lab […]

New C2c2 CRISPR Turns The Tables on RNA

June 15, 2016

In the CRISPR hype up to now, DNA has gotten a raw deal. In all known CRISPR systems, RNA guides gang up with protein effectors (e.g., Cas9 and Cpf1) to chop up poor, abused DNA helices. Now, a new CRISPR protein – C2c2 – is giving DNA a reprieve, turning the tables on RNA instead. […]

Freeze-Dried, Zika-Detecting Gene Circuits

June 15, 2016

Freeze-drying has claimed to be the technology the future before, but its fruits – from strawberries to ice cream – have never quite lived up to the hype. However, synthetic gene circuits recently joined the picnic with a powerful new use for the process; they can be freeze dried onto filter paper along with cell-free […]