Webinar: Whole-genome Insights into Cancer as a Dysregulated Epigenome Allowing Cellular Growth Advantage at the Expense of the HostMarch 10, 2014Dr. Andrew Feinberg discusses recent work that has shed new light on the epigenome and it’s role in cancer. Abstract: We and our collaborators have been developing efforts toward whole genome approaches to epigenetic analysis of human disease, including array-based analysis and whole genome bisulfite sequencing. Surprising results have been the discovery of CpG island shores and large hypomethylated […]
Webinar: Genetic Analysis of the Physiological Roles for lncRNAs in DevelopmentMarch 8, 2014Loyal A. Goff, Ph.D presents his research on: Genetic Analysis of the Physiological Roles for lncRNAs in Development Abstract: Many studies are uncovering functional roles for long noncoding RNAs (lncRNAs), yet few have been tested for in vivo relevance through genetic ablation in animal models. To investigate the functional relevance of lncRNAs in various physiological […]
Great Deals on Insight Pharma’s Epigenetics ReportMarch 5, 2014Our friends at Insight Pharma Reports created an exclusive deal, just for EpiGenie readers: Get 25% off of their new epigenetics report. This is a must have for anyone that needs to stay in tune with the epigenetics research market. There, now don’t you feel special? Epigenetics: Emerging Targets, Available Technologies, Expert Interviews, and an […]
DNA Methylation Reveals Your True AgeFebruary 28, 2014To the utter dismay of Hollywood actresses and men in the throes of a mid-life crises, the Epigenetic Clock has just chimed in to remind us that there really is no escaping time. A new report from Carola Weidner and team at Aachen University in Germany has just shown that, sort of like counting the rings in a […]
CRISPR-Cas, Zinc Fingers and Epigenetic Editing with Dr. Marianne RotsFebruary 27, 2014Epigenetic Editing is an emerging field that has sparked interest across a number of research groups. By using a fusion of TET we can now target specific genomic regions for demethylation in order to learn about their function and regulation. We got in touch with one of the field’s experts, Dr. Marianne Rots, commissioning editor of Clinical Epigenetics, […]
Cells Take Epigenetic Cues from Tissue Environment, TooFebruary 19, 2014A ton of time and effort has been spent recently to detail how the external environment can shape our epigenome, but now Peter Jones and company at USC show that we shouldn’t underestimate the power of our internal environment. In a new published report, the USC team found that the extracellular cues taken from the surrounding tissue […]
DNA Methylation Detection In the Palm of Your HandFebruary 19, 2014Thanks to our never-ending obsession with miniaturizing technology and competitions like the Tricorder X-prize, it looks like everyone’s favorite piece of Star Trek medical paraphernalia, the Tricorder, may be just around the corner. A team from the University of Queensland has developed a new micro-device that creates a simple, rapid, and inexpensive strategy for detecting DNA […]
Go Into the Light With Promega HDAC-Glo™ 2/IIa AssaysFebruary 18, 2014Searching for that next great HDAC inhibitor can be a grueling task, but now the R&D team at Promega has just introduced the HDAC-Glo™ 2 and IIa Assays to make your HDAC screening life a whole lot better. Just like the rest of the HDAC-Glo™ Assay family, the HDAC-Glo™ Class IIa and HDAC-Glo™ 2 Assays […]
NOMe-Seq Secrets RevealedFebruary 17, 2014You’ve read the NOMe-seq (Nucleosome Occupancy and Methylome sequencing) papers. Seen the splashy advertisements. Now, we’ve consulted with the experts at Active Motif to get the inside scoop on how to get started, and get the most out of your NOMe-seq experience. NOMe-Seq was originally published and developed by researchers in the Peter Jones lab […]
Epigenetics Special Issue: Non-coding RNAs in Epigenetic RegulationFebruary 17, 2014From the very beginning, EpiGenie has held a place in our hearts for non-coding RNAs. That’s why we were stoked to see that the Landes journal Epigenetics dedicated an entire issue to the enigmatic and always interesting little transcripts. The Epigenetics: Special Focus on Non-coding RNAs in Epigenetic Regulation issue features a boatload of reviews […]