The Return of the Coding RNAsNovember 7, 2011When George Lucas penned the scripts to the Star Wars series, is it possible that he foresaw the parallels his plots would have with epigenetics? Probably not, but some new research has us thinking they share a lot in common. The non-coding RNA “dark side” of the genome has generated a lot of buzz over the last […]
EpiGenie Review: Environmental Links to Epigenetics and CancerOctober 27, 2011If our daily environment can lead to cancer, and it can also alter our epigenetics, then it only makes sense that there is a connection between all three things. Here are the articles EpiGenie has written about showing the evidence linking environmental factors, and epigenetic mechanisms together with cancer. Environmental – Epigenetic Link to Cancer […]
Epigenetic Fountain of Youth Found in Worms?October 26, 2011We recently came across a hot new article that even the mainstream media has been all over. Stanford University researchers found that longevity can be passed down through generations without using DNA sequence to do it. The study found that C. elegans worms with certain histone modifications leading to increased longevity were able to pass that long […]
RNA Demethylation in ObesityOctober 19, 2011In news more surprising than the rise of the Occupy Wall Street movement, researchers have unearthed a novel mechanism in which RNA demethylation is mediated by, of all things, the obesity related protein FTO. FTO is a well-established target of obesity and diabetes researchers, but its function has so far been elusive. At least it […]
Shhh! RNAi Silences Yeast Heterochromatin As Cells DivideOctober 18, 2011It’s too bad that a little RNA interference (RNAi) won’t quiet down those noisy neighbors, but apparently it does the job quite well on yeast heterochromatin. Researchers from Cold Spring Harbor report that RNAi helps promote the silencing of heterochromatin during DNA replication (“S” phase), and they figured out how it all goes down in […]
Melt Away the Stress with miR-34October 12, 2011Every day there’s so much to stress about: Will your next big experiment be a success? Can you get your grant application in on time? How can Lady Gaga possibly outdo her last awards show outfit? Apparently, mice have stressful lives, too, and a recent study suggests that a particular miRNA, miR-34, might help them […]
Born to Lose: Histone Mods Tag Stem Cells for DNA Methylation of miRNA Loci in CancerOctober 12, 2011It’s usually not hard to spot when things seem like they’re destined for failure. Like you ne’er do well cousin, or an American car from the 80’s. Other times, closer examination is required to find the seeds of a problem. That’s what it took for scientists to uncover how some harmless embryonic stem cells (ESCs) […]
Baby Epigenomes Thank You For Not SmokingOctober 10, 2011It’s no secret that smoking is bad, now new evidence shows that smoking during pregnancy could be very dangerous for a fetus. In a recent report, Baylor College of Medicine researchers found that moms who light up are also altering their babies’ epigenomes and transcriptomes. In some previous work, the scientists had only looked at […]
EpiGenie Review: Epigenetic Cancer Therapies and DiagnosticsOctober 10, 2011Nearly everyone has been affected by cancer in some way or another. That’s why we’re so stoked to see all of the amazing breakthroughs in cancer knowledge coming from epigenetic research these days. Will it lead to treatments or cures anytime soon? Who knows, but it sure seems like we’re on the right track. Just […]
X-linked miRNAs Give Fairer Sex Unfair Immune AdvantageSeptember 28, 2011We love it when Epigenetic research hits the mainstream media, if for no other reason than our family and friends will have some idea of what we’re talking about when they ask about our work. This new article from sceintists at Ghent University in Belgium definitely fits the bill. Their new research finds that X-linked […]