Cells Take Epigenetic Cues from Tissue Environment, TooFebruary 19, 2014A ton of time and effort has been spent recently to detail how the external environment can shape our epigenome, but now Peter Jones and company at USC show that we shouldn’t underestimate the power of our internal environment. In a new published report, the USC team found that the extracellular cues taken from the surrounding tissue […]
DNA Methylation Detection In the Palm of Your HandFebruary 19, 2014Thanks to our never-ending obsession with miniaturizing technology and competitions like the Tricorder X-prize, it looks like everyone’s favorite piece of Star Trek medical paraphernalia, the Tricorder, may be just around the corner. A team from the University of Queensland has developed a new micro-device that creates a simple, rapid, and inexpensive strategy for detecting DNA […]
Go Into the Light With Promega HDAC-Glo™ 2/IIa AssaysFebruary 18, 2014Searching for that next great HDAC inhibitor can be a grueling task, but now the R&D team at Promega has just introduced the HDAC-Glo™ 2 and IIa Assays to make your HDAC screening life a whole lot better. Just like the rest of the HDAC-Glo™ Assay family, the HDAC-Glo™ Class IIa and HDAC-Glo™ 2 Assays […]
NOMe-Seq Secrets RevealedFebruary 17, 2014You’ve read the NOMe-seq (Nucleosome Occupancy and Methylome sequencing) papers. Seen the splashy advertisements. Now, we’ve consulted with the experts at Active Motif to get the inside scoop on how to get started, and get the most out of your NOMe-seq experience. NOMe-Seq was originally published and developed by researchers in the Peter Jones lab […]
Epigenetics Special Issue: Non-coding RNAs in Epigenetic RegulationFebruary 17, 2014From the very beginning, EpiGenie has held a place in our hearts for non-coding RNAs. That’s why we were stoked to see that the Landes journal Epigenetics dedicated an entire issue to the enigmatic and always interesting little transcripts. The Epigenetics: Special Focus on Non-coding RNAs in Epigenetic Regulation issue features a boatload of reviews […]
Environmental Epigenetics TimelineFebruary 11, 2014Thanks to growing interest from the general public, environmental epigenetics is a red-hot topic with no signs of cooling off anytime soon. We’ve certainly covered our fair share of research with an environmental slant to it, so if you want to review, research, or just plain get up to speed on the subject, these articles […]
SIRT1, miR-34a Clear Out the JNK from Fatty LiversFebruary 11, 2014When it comes to liver disease, it seems most of the attention (and research) goes to the variety that is associated with the consumption of alcohol. While that’s a big concern for those of us enjoy the occasional adult beverage, it’s left non-alcoholic fatty liver disease (NAFLD) under-studied. But now that’s changing. According to Rui […]
Clinical Epigenetics TimelineFebruary 10, 2014The underlying goal for most epigenetic research projects is to eventually lead to a therapeutic clinical application. Here we provide a history of clinical epigenetic advances in this interdisciplinary field as told through our articles and Conference Highlights.
Epigenetics of Cancer TimelineFebruary 9, 2014Epigenetic mechanisms have been studied in cancer for decades. Unfortunately, we haven’t been around that long, but check out these great articles that capture the recent history of epigenetic breakthroughs in cancer.
The Rise of lncRNAs TimelineFebruary 9, 2014Long non-coding RNAs, also known as lncRNAs, are gaining a truck load of momentum in the field of the epigenetics. Here we highlight the hottest research, methods papers, and the occasional interview centered around these long and curvy regulatory RNAs.