epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

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Children Prenatally Exposed to Cannabis Have Altered DNA Methylation

October 7, 2024

As more states legalize and decriminalize cannabis, more questions are being raised about its effects, especially on pregnancy. Now, a clear-thinking team sees through the haze and shows that maternal cannabis use during pregnancy is associated with epigenome-wide differential DNA methylation in the blood of exposed children, especially in genes involved in neurodevelopment. Studies have shown […]

Epigenetic Two-factor Authentication Secures Male Fertility from the Insider Threat of Transposons

October 7, 2024

Two-factor authentication represents a modern approach to securing our digital lives from outside threats; however, research now suggests that this concept may not be so modern. A new study now reveals that male germ cells employ a piRNA-mediated epigenetic “two-factor authentication” strategy to secure the precisely timed DNA methylation-induced silencing of insider threats that impact […]

Metformin Keeps Aging Primate Epigenomes “In Form”

September 30, 2024

Those of us feeling the all too familiar effects of time may look to cut back on certain “excesses” and keep fit (in both body and mind) to maintain a healthy aging process. Now, a team of fitness enthusiasts has revealed that long-term treatment with the diabetes drug metformin maintains an aging population of monkeys […]

Amyloids Could Solve the ‘Missing Heritability’ Mystery

September 23, 2024

Science is full of mysteries just waiting to be solved. One of these mysteries is the “missing heritability” problem—it turns out that some traits seem hereditary, yet cannot be traced back to nucleic acids or even known epigenetic modifications. Now, a talented team studying C. elegans has spotted protein clumps called amyloids that could be […]

Genome-Wide DNA Methylation Changes from Vaping and Smoking Have Striking Similarities

September 3, 2024

Vaping has been touted as a safer alternative to smoking, but some recent studies are showing that the biological effects have similarities. Now, a team clears the air and reports that DNA methylation changes in vapers’ oral cells resemble those found in smokers, which suggests that vaping could have comparable long-term health effects. Smoke gets in […]

Epigenetic Machinery Fights Back! SARS-CoV-2 RNA Modifications Inhibit Replication and Pathogenesis

September 3, 2024

Recent reports have highlighted how SARS-CoV-2 infection and the resulting COVID-19 can turn epigenetics against us; however, new research now reveals that the epigenetic machinery can also help us fight back against viral attacks – in the guise of specific RNA modifications. A team of epigenetic tusslers guided by Yu Chen (Wuhan University) knew of […]

Chrom-seq Uses ‘Readers’ to See Which RNAs Put Epigenetic Marks on Chromatin

August 20, 2024

Reading glasses, or “readers,” help you see text and other fine details up close. Inspired by our desire for increased resolution, a talented team is using histone readers to more clearly see which long noncoding RNAs (lncRNAs) interact with particular histone modifications. Their method, called Chrom-seq, doesn’t require highly pure antibodies or crosslinking, making it […]

Histone Serotonylation: From Boosting Moods to Regulating Brain Tumor Progression

August 19, 2024

While many know that serotonin impacts mood and emotions, a smattering of studies have found that this neurotransmitter can modify histones and regulate gene expression. Now, fascinating new research reveals that histone serotonylation contributes to the regulation of aggressive brain tumors, playing a role in the complex interactions taking place between neuron–tumor signaling, epigenetics, and […]

Keeping up With Epigenetic Clocks: PRC2-AgeIndex Measures Gains of DNA Methylation Across the Genome

August 6, 2024

While it may seem like it’s harder to keep up with epigenetic clocks than with the Kardashians, this is one you’re not going to want to miss. Many epigenetic clocks people use to assess aging are built on the DNA methylation status of a few CpGs, and it’s unclear how these sites are related to […]

CoRSIVs in Cows? Targeting a DNA Methylation Bullseye May Improve Livestock Farming!

August 5, 2024

Finding informative epigenetic targets in the genome is no easy task; however, cleverly composed studies previously reported on the discovery of correlated regions of systemic interindividual variation (or CoRSIVs) in humans – DNA methylation patterns that vary between individuals but remain consistent across tissues. Now, this talented team sets its sights on understanding this level […]

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