epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

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DNA Methylation qPCR Panels Keep Stem Cells in Check

May 8, 2012

Every day, in labs all over the world, stem cells are changing. Sure they may lack (lineage) commitment, but these ultra-promising cellular blank canvases aren’t living sedentary epigenetic lifestyles. DNA methylation in stem cells is on the move with age and passages and you might not even know it. Sequencing still isn’t quite feasible for […]

oxBS-Seq Breaks Through 5hmC Sequencing Barrier

April 26, 2012

5-Hydroxymethylcytosine (5hmC) has always been a bear to sequence, mostly because it’s virtually indistinguishable from its close relative, 5-methylcytosine (5mC) using classic bisulfite sequencing techniques. Now a new sample preparation method has hit the scene that can discriminate between cytosine, 5mC and 5hmC at single base resolution, called oxidative bisulfite sequencing (oxBS-Seq) that essentially smashes […]

Sequencing DNA Methylation Past, Present, Future with Dr. Wolf Reik

April 26, 2012

Dr. Wolf Reik discusses the challenges in DNA methylation sequencing and the next big swings in epigenetic modification sequencing and discovery. This interview took place at the Keystone Symposia’s Epigenomics and Chromatin Dynamics joint meeting in January, 2012. This video was brought to you by epigenetics supporters at EMD Millipore. Sequencing DNA Methylation […]

Argonaute AGO2 Gives miRNAs a Little Trim Around the Edges

April 17, 2012

Isn’t there always one person in a group of friends who’s a little weird or different? It turns out that AGO2, is a little different from its Argonaute paralogs, AGO1, 3, and 4. Researchers in Singapore are reporting that unlike other Argonautes, oddball AGO2 trims mammalian miRNAs, changing their functions during development. The team knew […]

miRNAs Decide Which Honey Bees Do Which Honey-Do’s

April 17, 2012

It seems nobody has been busier than the honey bee lately when it comes to being a model epigenetic organism. (Watch your back c. elegans!) Over the last year or so, we’ve seen how HDAC inhibitors affect the bee caste system, as well as how social cues alter DNA methylation patterns in the brains of […]

Active Motif MeDIP-Seq Services Will Put You On the Right MethylPath™

April 17, 2012

Let’s say you want to get the ball rolling for studies on a new disease. You know you want to search for any important changes in methylation patterns; but with a whole genome worth of ground to cover, how do you decide where to look first? Active Motif now offers the MethylPath™ MeDIP-Seq Service that […]

Recorded NIH Webcast with Dr. Randy Jirtle: Epigenetics-How Genes and Environment Interact

April 17, 2012

The interplay between epigenetics and the environment is one of many fascinating research areas of epigenetics. If you were lucky enough to attend Keystone Symposia’s Meeting on Environmental Epigenomics and Disease Susceptibility last spring, you were fortunate enough to hear from some of the world’s top researchers leading the way to a better understanding of […]

Colon Cancer Signs on the Dotted Line with Epigenomic Enhancer Signature

April 16, 2012

Handwriting experts say that someone’s signature reveals a lot about their personality. Whether these analyses are “scientific” is debatable, but researchers in Ohio and New Hampshire have evidence that they’ve identified a signature of enhancer histone modifications that points to colon cancer. Mono- and dimethylated H3K4 marks many classes of enhancers, so the team did […]

Tackling the Dimensions of Chromatin via 3C with Dr. Job Dekker

April 12, 2012

Dr. Job Dekker discusses trends that he sees in chromatin structural studies, Chromosome Conformation Capture (3C), and bringing a multidisciplinary approach into the lab to better understand chromosomes. This interview took place at the Keystone Symposia’s Epigenomics and Chromatin Dynamics joint meeting in January, 2012. This video was brought to you by epigenetics supporters […]

ChIP & Bisulfite-Seq Cut Through Chromatin, DNA Methylation Chatter

April 4, 2012

There are two sides to every story. Maybe even more if you ask a lawyer. So it only makes sense that two epigenetic mechanisms like chromatin and DNA methylation would each have something to say about the genomic regions they regulate. Two new methods each combine ChIP and bisulfite sequencing in order to cut through […]

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Epigenetics and ncRNA Headlines

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