epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

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DANPOS Reveals Dynamic Nucleosomes

January 2, 2013

Keeping track of where some nucleosomes are on chromatin can be just as tricky as keeping track of Taylor Swift’s love life. They’re on, they’re off, they’re at a new place. Well, here comes a new bioinformatics solution to help you keep score on the nucleosome front, anyway. It’s called DANPOS, and it provides single-nucleotide […]

Watch Chromatin “Breathe” in Embryonic Stem Cells

December 31, 2012

This holiday season, we breathed in lots of good smells—the scent of pine trees, the aroma of pumpkin pie, and the unmistakable smoky smell of a roaring fire. Now, researchers say they’ve caught chromatin in the act of “breathing” in human embryonic stem cells (hESCs) before they differentiate. The team from California and Italy developed […]

Top Epigenetics & ncRNA Conference Picks for Winter 2013

December 27, 2012

We’re on the verge of 2013. For those of you who want to up your epigenetics research game and have some fun in the process, we’ve got conferences you should definitely check out. The year starts off a little quiet on the numbers front, but the quality more than makes up for it. January […]

Get Tissue-Specific with EMD Millipore’s CpGenome™ 5-hmC Quantitation Kit

December 26, 2012

One of the few things epigenetics researchers know for sure about 5-hmC, is that it’s highly variable amongst different types of tissues and cell types. So where does your favorite sample fall on the 5-hmC quantity spectrum? Thanks to the new CpGenomeTM 5-hmC Quantitation Kit from EMD Millipore that question is easier than ever to […]

EMdeCODE Deciphers Epigenetic Code, Finds New Role for Old Histone Modifications

December 19, 2012

With all the “LOL”s, “IMHO”s, and “YOLO”s out there, it’s like we’re all speaking in code. When we get stumped on what these things mean, we can always turn to Google. But what if you want to decipher the hypothetical “epigenetic code?” Well, one researcher has the answer—EMdeCODE, a new algorithm that does just that […]

Hypermethylation in miRNA 26a Provides New Route in Prostate Cancer Progression

December 12, 2012

There’s usually more than one right way to get where you want to go. Unless of course, you’re using Apple Maps, then all routes are questionable, but at least have a pretty interface. It turns out there are at least two ways to wind up with prostate cancer, and neither are that attractive—having a gene […]

5hmC Analysis Timeline

December 10, 2012

EpiGenie has probably covered developments in 5hmC more than any topic the last couple of years, so we’ve compiled this timeline for you. Scroll along to see what you may have missed if you’ve been out of the loop or lab for a sabbatical.

New and Improved: Multiplexed Reduced Representation Bisulfite Sequencing (RRBS)

December 7, 2012

These days, we’re all about multi-tasking—talking on our cell phones while placing our cappuccino order at Starbucks and tweeting about it all on our tablets. In that same vein, researchers report an optimized protocol for multi-tasking (well, technically “multiplexing”) reduced representation bisulfite sequencing (RRBS) for ramped-up DNA methylation data. RRBS is great, churning out methylation […]

The Daily Rhythms of Transcription and the Epigenome

December 7, 2012

We all have a daily routine. For much of the EpiGenie office staff, that includes getting out of bed, brushing our teeth, going to work, grabbing a coffee, clocking a few hours on Facebook and complaining that there aren’t enough hours in the day. Now, researchers say that transcription and epigenetic modifications in mouse liver […]

Low Cell ChIP-Seq

November 28, 2012

Chilly, wintry temps have us longing for palm trees, sandy beaches, and the limbo call of “How low can you go?” Researchers in Norway and Germany have the answer—and a new ChIP-seq method that allows them to analyze genome-wide DNA-protein interaction data for samples that have very few cells, without culturing (which could alter epigenetic […]

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