epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

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Exploring the Genotype-Chromatin Structure-Disease Risk Connection

July 26, 2012

Its easy to obsess over little details, and want to understand every nuance of a subject that you’re passionate about, but sometimes it’s helpful to step back and get a broader perspective on what you’re working on. This review article from Richard Meagher and Kristofer Müssar at the University of Georgia does just that by […]

More Epigenomic Differences Found in Twins?

July 24, 2012

Twins may look alike, and even share identical genomes, but according to new studies, their epigenomes can be surprisingly different. Examination of the DNA methylation patterns in sets of twins revealed that early environmental conditions can alter epigenomes, and have a big impact on individual variability. A research effort headed up by Jeff Craig and […]

Guide: Quick Tips for ChIP Beginners

July 17, 2012

At Abcam we run quite a few ChIP assays and we interact with customers that run even more than us. Lately, we’ve noticed that more researchers are turning to ChIP for the first time as gene regulation studies continue to grow. So we thought we’d share a couple of quick tips for various aspects of […]

Pushing the Technology Frontier in Epigenetics Research with Dr. Andrew Feinberg

July 16, 2012

Dr. Andy Feinberg discusses what technology advances are needed in the field of epigenetics. This interview was shot on campus at Johns Hopkins University. This video was brought to you by epigenetics supporters at EMD Millipore Single Cell Analysis One of the areas I think is going to be really important is single-cell analysis. […]

ChIP Principles and Troubleshooting with Dr. Karen Halls

July 16, 2012

This webinar delivered by Dr. Karen Halls covers and introduction to chromatin and the ChIP process. It reviews protocols for ChIP, antibody selection, optimization of the method and includes troubleshooting guidance.

Guide: Simple Tips to Boost Your Bisulfite-Based Applications

July 11, 2012

Bisulfite conversion remains a key player in almost every study involving DNA methylation. Since DNA methylation is emerging as a key mechanism in a diverse range regulator processes and disease mechanisms, many researchers new to the field are turning to bisulfite-based analyses that might not be experts in the approach. We’ve been optimizing bisulfite […]

Step Up Your Bisulfite: DNA Methylation Analysis Tips for Challenging Samples

July 11, 2012

Sooner or later researchers studying DNA methylation turn it up a notch and get into some difficult sample scenarios, where the interesting data hides tucked away. We caught up with the R&D scientists at Zymo Research to hear more about some of the challenges that researchers face when stepping up into some of these sample […]

Free White Paper: Genome-Wide Analysis of RNA-Protein Interactions

July 3, 2012

Nowadays, with RNAs interacting with chromatin interacting with DNA methylation marks, researchers are keener than ever to get their gloves dirty with RNA Immunoprecipitation (RIP). If you fit that bill, then you’ll want to check out this white paper authored by Dr. André P. Gerber out of the Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland. […]

Wrapping Your Mind Around Brain DNA Methylomes

June 28, 2012

Not much is known about the normal DNA methylation differences between functionally different parts of the brain or how they relate to the patterns in peripheral tissues like blood. In a new study, scientists extensively mapped out the brain methylome to create a baseline resource for use in future research efforts. Researchers from King’s College […]

TACh Method Unlocks Chromatin Accessibility in Clinical Samples

June 28, 2012

Biobanks store valuable clinical samples that could provide a wealth of information about health and disease, but the secrets contained in these samples have been tough to get at with current technologies. But now, NIH researchers report a rapid new method called Tissue Accessible Chromatin (TACh) that could unlock these precious samples for chromatin analyses. […]