epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

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Astronomical Findings from the NASA Twin Study on the Effects of Space Flight

May 6, 2019

Identical twins are known for having some pretty out of this world similarities. Picking the same clothes, feeling the other’s pain, and often going into the same careers. The latter is true for Mark and Scott Kelly, monozygotic twins who also both happen to have been trained as astronauts. Twins are a favorite model system […]

Members of the PIWI League Play Important Positions in the Brain

May 3, 2019

It takes a special kind of small RNA to try out for the PIWI team. PIWI-interacting RNAs (piRNA) are small, have and adenine at their 10th position, an uracil at their 5’ end, and 2’-O-methylation at their 3’ end. This unique physique helps piRNA work with PIWI proteins to defend the germline against an aggressive transposon offense, but […]

New Epigenetic Clock Offers an Evolutionary Conserved View of Aging Through Ribosomal DNA Methylation

April 27, 2019

With updates and novel iterations to the “epigenetic clock” occurring at a pace faster than our smartwatches, it’s about time a new player emerged in the world of epigenetic clocks. Not only can these specialist timepieces keep track of our chronological age, but they can also tell us how environmental factors affect the pace of […]

Giving Identity to the Masses: Antisense lncRNA Transcription Facilitates DNA Demethylation to Determine Promoter Choice

April 21, 2019

As modern technology develops, we grow increasingly connected with one another while also striving to maintain our individual identities. Although some may blame social media for our desire to be unique snowflakes just like everyone else, exciting new research demonstrates a molecular mechanism for individual neuronal identity in the brain that may just be the […]

The Relationship Between CTCF and DNA Methylation? It’s Complicated…

April 16, 2019

Everyone knows one of those couples who keeps getting together and breaking up, as if they’re trying to decide how much they like each other. Well the chromatin architectural protein CTCF and DNA methylation have one of those relationships, and it just got more complicated! For years, we’ve been trying to decipher whether DNA methylation always prevents […]

Sugar Sticks it to Histones and Causes Problems for Chromatin Architecture

April 15, 2019

Many of us have been lectured by our dentist about eating those delicious, sticky candies. Now, as it turns out, those cavity-causing sugars not only stick to your teeth but can stick to your histones too! Through a non-enzymatic process known as glycation, a glucose group is covalently attached to specific amino acids, which can […]

Reactivating “Fossil” Enhancers from Embryonic Development in Adult Tissues

April 10, 2019

The Jurassic Park movies got the whole world excited about resurrecting dinosaurs from fossilized DNA, but more recent findings that the half-life of DNA is only 521 years mean that dream is science fiction. So, while the finer details of dinosaur genomes may be lost in the fossil record, new work has dug up epigenomic […]

Histone Demethylases Have a “Sixth Sense” about Oxygen Levels!

April 7, 2019

Many people make dubious claims of being endowed with more than the five traditionally recognized senses; their “sixth sense” providing the extrasensory perception needed to converse with spirits and ghosts and predict the future, among other fanciful claims. While there is a lack of any evidence for extrasensory powers and paranormal activity, robust studies have […]

Inflammation in the Information Age: Multi-Tissue Chromatin and Transcriptional States of Mammalian Aging

March 26, 2019

We’re living in the information age―the age of supercomputers, big data, and machine learning―and the epigenetics field is capitalizing on these capabilities. New research from the lab of Anne Brunet at Stanford University harnesses the power of the ‘information age’ to provide insight on the ‘inflammation age’―that is, changes in the epigenetic landscape that lead […]

Histone Methylation Has a New Sidekick and Its Name is Serotonin!

March 17, 2019

Watch out epigenomic evil-doers, histone H3 has a new sidekick to help it keep gene regulation in shape. By day, serotonin can be found in its traditional role as a neurotransmitter; being released by cells of the nervous system and binding to specific receptors to impact a wide range of functions, from cognition to gut motility. […]

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Epigenetics and ncRNA Headlines

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