epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

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A Suite of New Tools to Solve Single-cell Epigenetic Enigmas

December 23, 2021

Welcome explorers of the epigenome! Are you looking for new tools to help answer the toughest of epigenetic enigmas? Then check out this suite of single-cell methods papers from technologically-talented teams led by Aviv Regev (Broad Institute of MIT and Harvard) and collaborators. inCITE into How Transcription Factors Shape In Vivo Gene Expression A collaboration […]

A Youthful Brain Boost via DNA Hydroxymethylation: TET1 Enters the Myelin Repair Technician’s Toolkit

December 13, 2021

Does it feel like your aging brain cells have been firing a little slower lately? Why not refresh your connection and speed up your synaptic signal transmission with a visit from your oligodendrocyte myelin repair technicians. Their youthful TET1 and DNA hydroxymethylation repair kit will bring you back to fiber-optic speeds in no time. This […]

A Circulating microRNA Makes a Macro Difference in the Battle Against COVID-19

November 28, 2021

From holding the door open to passing on a link to an exciting epigenetics paper – small gestures can make an enormous difference to anyone’s day! Now, an exciting new study suggests that the expression of a microRNA has a macro impact during SARS-CoV-2 infection and could represent an important target for the treatment of […]

Automated Chromatin Profiling Platforms Autopilot Patients to the Clinic

November 22, 2021

From human-free supermarket check-outs to autopiloted cars, the modern world is rapidly moving towards automation. In the most recent advance, a rabble of robotic researchers has applied related technological tricks to epigenetic assays to “autopilot” high-throughput chromatin profiling and provide a clinical tool that may support optimized treatment choices in leukemia patients. Specifically, a technology-driven […]

Epigenetics Takes the Wheel as the Brain Mapping Project Gets Motoring!

October 30, 2021

It’s easy to get lost when motoring down the epigenetic landscape; thankfully, a group of cunning cartographers from the Brain Research through Advancing Innovative Neurotechnologies Initiative Cell Census Network (or BICCN for short) has generated single-cell maps to guide your voyage of the brains’ motor cortex. Although this epigenetic road trip may be too long […]

Transgenerational Epigenetic Inheritance of Horizontally-transferred Memories Goes Viral

October 4, 2021

While research into the transgenerational epigenetic inheritance went viral long ago, a new “social media” platform powered by horizontal transfer has taken “going viral” a bit too literally. In their retweetable new article, researchers from the lab of Coleen T. Murphy (Princeton University, New Jersey) now demonstrate that virus-like particles (VLPs) support horizontally-transferred memories and […]

scSPRITE Adds a Twist to Single-cell Genome Organization

September 27, 2021

Are your single-cell chromosome conformation capture experiments looking a little flat? Is your Hi-C data missing that “pop”? Well, don´t fret; a new study serves up a refreshing twist on a popular technique – scSPRITE – that will put some fizz back into your single-cell genome organization research! While bulk profiling provides an averaged read-out […]

CRISPR-EChO Amplifies the Sound of Silent Chromatin

September 6, 2021

Hello heterochromatin, my old friend; CRISPR has come to edit you again; And echo in the sound of silence. As reported in a resounding new study, CRISPR-EChO comes at you from the lab Stanley Qi (Stanford University, California) and amplifies the sounds of silent chromatin. Following on from avant-garde studies describing CRISPR-GO and CasDrop, which […]

The Intergenerational Effect of Paternal Stress: circRNAs Join the Blame Game

August 23, 2021

Although we’ve known for a while that paternal stress can lead to problems down the road for their offspring thanks to DNA methylation and histone modifications, non-coding RNAs have now come full circRNA. In their latest, a talented team from the lab of Eric Miska (University of Cambridge, UK) decided to find out which RNA […]

Supersizing Crops by Demethylating RNA – A New Way to End World Hunger?

August 23, 2021

While supersizing meals has helped to expand the waistlines of many a human “couch potato,” a seriously sumptuous new study has established that RNA demethylation induced via the expression of the human RNA demethylase FTO in potatoes results in a supersizing that could help end world hunger. The transformation of exogenous and endogenous genes has […]