epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

Search Articles

Going ChIP-less Yields More Insights on Histone Code Combos

April 29, 2014

When it comes to studying chromatin structure and histone modifications, a new technique proves that sometime less really is more, ChIP-less that is. Antibodies for individual histone post-translational modifications (PTMs) have long been the star of chromatin technology, but PTMs often act in concert to form a dynamic histone code whose combinations can interfere with antibodies attempting to bind […]

Ancient History as Told by DNA Methylation

April 23, 2014

To some people ancient history is anything prior to Facebook, for others, it might mean pre-iPod, but this new study uses DNA methylation to look WAY back in time and analyze the beginnings of human evolution (And yes, that’s before the internet was invented). Using epigenomics to look back into pre-historic times has taught us […]

DNA Cubes May Take Genome Editing Outside the Box

April 22, 2014

Through the use of some creative chemistry researchers have devised DNA cubes that can deliver molecular packages with precision that would make FedEx jealous. A geometrically genius team from McGill University crafted a piece of DNA origami that will only release it’s molecular payload when triggered by a specific mRNA. Here’s how they did it: Cubes were […]

Kit Competition Reveals Hacks to Help Bisulfite Conversion

April 16, 2014

At first pass it may seem like all bisulfite conversion kits are essentially the same – and for the most part, that’s true. But according to a recently published evaluation, the conversion is all in the details, and if those are overlooked it can have a big impact on the results. Fortunately, researchers from the […]

SIF-seq Sifts Out Stem Cell Enhancer Gold

April 10, 2014

Searching for functional enhancers is sort of like panning for gold; there is enormous potential for riches, but the task is akin to finding a needle in a stack of needles. A team from the Berkeley National Laboratory decided to apply their own gold rush-style, enhancer mining techniques to develop a new method for the discovery of functional enhancers aided […]

Mood Killer: DNA Methylation Linked to Depressive Disorder

April 10, 2014

There aren’t a lot of laughs to be had when discussing the very real and increasing problem of depression, but some new research supported by the brain initiative on sets of twins may help to lighten the mood a bit. Studies have begun popping up showing that epigenetic marks can be used to show if someone has […]

Zymo Research Converts Sequencers into Epigenetic Analyzers

April 7, 2014

Next-Gen Sequencing (NGS) has revolutionized scientific research, but when it comes to epigenetic exploration, scientists have had to make do with sequencing library prep methods from other non-epigenetic applications. The crew at Zymo Research has found a way to adapt sequencers for epigenetic research, without having to completely retrofit the instrument. With the introduction of […]

Take the BS Out of Bisulfite Data Analysis with the DMAP Analysis Suite

April 2, 2014

Tools and databases always make mapping our world a little easier, whether its used to train as Google’s next pokemaster or figuring out what to do with your heaps of fancy new reduced representation bisulphite sequencing (RRBS) or whole genome bisulphite sequencing (WGBS) data. A talented team of epigenome hackers from the University of Otago (New Zealand) have just put […]

Histone Code Tips the Scales of Development

March 31, 2014

All of life is a balancing act. Whether you’re walking the tight-rope in a circus, or the epigenome regulating gene expression its all about treading a fine line. Recently a team from the Institute of Medical Biology in Singapore found, while examining frog development, that there is an optimal ratio of the repressive histone H3 and […]

DNA Methylation Sorts Out Cell Type Heterogeneity

March 31, 2014

While all of our cells share an almost indistinguishable genome, the variation created by the epigenome makes sorting and tackling the heterogeneity of cell types in your favorite homogenate a bigger task than finding a Yeti in a snow storm. Now a search and rescue team from Brown University has utilized DNA methylation profiles to breathe […]

Pages: 123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293949596979899100101102103104105106107108109110111112113114115116117118119120121122123124125126127128129130

TAP

Epigenetics and ncRNA Headlines

Featured Articles

Search Articles