epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

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Relax and Let NanoSPA Analyze m6A and Ψ RNA Mods for You

February 20, 2024

We could all use a spa day once in a while, so light some lavender-scented candles, take a deep breath, and let NanoSPA analyze the RNA modifications in your samples. This new nanopore sequencing analysis pipeline provides data on both N6-methyladenosine (m6A) and pseudouridine (Ψ) modifications at the same time, reducing stress and saving time. Instead […]

Making a Connection – Lactate Epigenetically Links Metabolism and Gene Expression

February 19, 2024

Falling in love, kicking a football, and cell identity changes driven by metabolic reprogramming all have one thing in common – making a connection is vitally important! Now, a well-hooked-up new study reveals how lactate epigenetically links metabolism to the activation of a gene regulatory network that controls embryonic development. A plugged-in team of researchers […]

TIME-Seq Flies When Constructing Cost-Effective Epigenetic Clocks

February 19, 2024

If time drags and money disappears when looking at DNA methylation-based epigenetic clocks, you are “in time” to hear of a newly described efficient and cost-effective bisulfite sequencing approach! Time flies – but money does not – with “tagmentation-based indexing for methylation sequencing” or TIME-seq! An on-time team led by David A. Sinclair (Harvard Medical […]

eBook: New & Novel Methods for Epigenetic Analysis

February 7, 2024

Epigenetics is not new, but methods used for analysis certainly can be! In this eBook, we take a look at, and present in a simple format, some of the hottest new methods for researchers looking at DNA Methylation, RNA modifications, Chromatin and Gene Regulation. Topics Include: Differential Methylation Data Are Quick, Easy, and Inexpensive with […]

GEMS Makes the m6A RNA Modification Shine in Living Cells

February 5, 2024

Unlike DNA or histone methylation, knowledge about N6-methyladenosine (m6A) modification of RNA is a little cloudy. It’s involved in some cancers and other diseases, but we don’t know as much about its expression in living cells. Now, a new method called GEMS makes m6A shine bright like a diamond for drug discovery and delivery of […]

Bilingual Proteins Establish and Maintain Heritable Silent Chromatin Domains

February 5, 2024

Whether you learn through hitting the books or traveling the globe – speaking two languages has many advantages. Now, a study into the basis of gene expression regulation reports how bilingual “read-write” proteins that “speak” two epigenetic languages can help us to learn about the complex mechanisms controlling sequence-independent heritable gene silencing. The dynamic duo […]

XIST’s X-istential Crisis: A New Role in Autosomal Gene Regulation

January 22, 2024

The long non-coding RNA (lncRNA) XIST functions as an epigenetic silencer tightly linked to the X chromosome to balance gene expression between the sexes; however, this lncRNA now has a cause for concern as an autosomal gene regulatory function just pushed XIST into a full-blown “X-istential” crisis! Reports have described a dispersed XIST configuration in […]

uCoTarget Is a Single-Cell Multiomics Method for Multiple Histone Modifications

January 17, 2024

Everyone loves a bargain, and a new method called CoTarget really delivers. It’s a method that delivers single-cell multiomics data on multiple histone modifications and transcription factors, as well as the transcriptome. It can easily scale up to analyze a million single cells, and unlike similar methods, it doesn’t require microfluidic devices or special transposon […]

SSSavi: Savvy Epigenome Editing with Diverse, Orderly Teams

December 12, 2023

Bringing in the right combination of people with different perspectives and abilities can take a team to new heights. And just like that savvy diverse team, a new epigenome editing tool called the Spy-Snoop-Sun-Avi (SSSavi) system recruits diverse effector molecules in an interchangeable and orderly way to understand how combinations of DNA and histone modifications […]

DNA Methylation Analysis Shows How Cannabis Exposure Increases the Risk of Adverse Health Outcomes

December 11, 2023

Do not risk missing a new paper describing a recent trans-ancestry epigenome-wide association study (EWAS) highlighting the significant health risks of recreational cannabis! In a fascinating new study, researchers now reveal that cannabis exposure can impact DNA methylation levels at specific regions independent of cigarette smoking to increase the risk of adverse health outcomes. Risk-averse […]

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Epigenetics and ncRNA Headlines

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