epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

Search Articles

Nature and Nurture Walking the Same Path?

February 11, 2010

Ever notice how it gets more interesting when there’s more than just black or white, love or hate, good or evil? The real action seems to take place in the gray areas. It seems true for methylated alleles as well. A recent paper looking into genomic imprinting found new evidence that both genomic and environmental […]

State of Methylome Analysis: Genome-Wide Methylation Techniques Review

February 11, 2010

The State of the Union Address and the drama/commentaries that accompany it have come come and gone, but a fresh Nature Review produced by USC’s Peter Laird now provides the epigenetics community with a State of Methylome Analysis. For the epigenetics researcher, it is every bit as insightful but won’t take as much time to […]

Histone Mods Choose Alternative Splicing Lifestyle

February 8, 2010

We can’t say we were surprised to hear that histone mods lead an alternative lifestyle—not that there’s anything wrong with that. It’s been theoretically shown that nucleosomes and their histone marks are involved in splicing by crunching data from previous experiments. Now, scientists at NCI, the University of Toronto, and the University of Texas Health […]

Methylome Stays Fashionable Throughout Differentiation

February 5, 2010

Our fashion sense evolves as we do. Just as you may trade your flip-flops for a business suit as you climb the corporate ladder, DNA methylation changes its style in cells that become more committed. To size up these methylation changes during differentiation, researchers at the UCSD Department of Reproductive Medicine and GIS in Singapore […]

Self Service Transcription Lane Now Open for miRNAs

February 2, 2010

Many retailers have opened up self-service checkout lanes lately, which are great for those customers with just a few items, or don’t want to get stuck behind the old couple who still pays with paper checks. According to a recent report, when it comes to transcription, at least some miRNAs might have the option to […]

In Evolution, Change Is the Only (Epigenetic) Constant

February 1, 2010

Most of us are thrown for a loop when conditions suddenly change, but some are better able to cope than others (we still haven’t gotten used to the new Facebook format). A recent PNAS paper by Johns Hopkins’ epi-gurus Andrew Feinberg and Rafael Irizarry makes the case that some of this adaptability stems from stochastic […]

Methylation Puts Nucleosomes in the Hot Seat

February 1, 2010

It’s no fun to get put in the “hot seat”. Whether it’s your advisor ragging on you for not having enough data; or your sweetie reminding you that you forgot your anniversary. Again. In either case, you sink lower and lower into your chair, and your muscles tighten while you take what you have coming. […]

Et Tu, Methyl Group? Epigenetic Betrayal of NSD1

February 1, 2010

Sometimes your best friend can become your worst enemy. Take the case of the methyl group and the histone methyltransferase enzyme NSD1: The methyl is NSD1’s little buddy through countless histone methyltransferase reactions, when suddenly the backstabbing little –CH3 teams up with a DNA methyltransferase to silence NSD1 expression. This tale of intrigue was told […]

Bisulfite Sequencing in Plants: Tips for “Going Green”

January 21, 2010

Figuring out human DNA methylation patterns with bisulfite sequencing can be tough, but the complexities of plant DNA methylation can turn your lab into a Little Shop of Horrors. That’s because plants methylate cytosine residues not only in the CG sequence context, but also in CHG and CHH (where H is any nucleotide but guanine). […]

Cancer Suppression is a miR-200 Family Value

January 21, 2010

Cancer regulation and the miR-200 cluster has been a family affair for a while now. A new article from a group at The University of Arizona highlights a couple of family members, miR-200c and miR-141, (they must be the attention-starved middle children) and how epigenetic regulation of their expression differs in normal and cancer cells. […]

Pages: 123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293949596979899100101102103104105106107108109110111112113114115116117118119120121122123124125126127128129130

TAP

Epigenetics and ncRNA Headlines

Featured Articles

Search Articles