epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

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96 Reasons To Love Millipore’s Magna ChIP™ HT96 Kits

April 4, 2012

Chromatin immunoprecipitation (ChIP) is the workhorse of the epigenetics world, like a penny-stock is to a Wall St. broker. So why run just one or two at a time? That’s so five years ago. Now that the EMD Millipore Magna ChIP™ HT96 kits are on the scene, you can churn out up to 96 ChIP […]

Schizophrenia’s DNA Methylation Fingerprints

April 4, 2012

By now, we’re all used to hearing about epigenetics in cancer or stem cell research, but its role in mental illness is still a pretty new concept. Understanding how exactly DNA methylation factors into schizophrenia may be a ways off, but new research promises to soon be able diagnose the condition through just a blood […]

Timeline for DNA Methylation in Mouse Development

April 4, 2012

Not everyone is onboard with the new Facebook timeline, but here’s a timeline you can really get into. Researchers are reporting the first genome-scale, base-resolution timeline of DNA methylation in the mouse embryo, including an analysis of the DNA methylation of oocytes and sperm. To do this, the team analyzed mouse oocytes, sperm, zygotes, early […]

Epigenetics Before Sequencing with Dr. Steven Henikoff

April 4, 2012

Dr. Steven Henikoff discusses interesting observations like chromosome puffs in polytene chromosomes back in the days before sequencing. This interview took place at the Keystone Symposia’s Epigenomics and Chromatin Dynamics joint meeting in January, 2012. Epigenetics Before Sequencing So when I was a graduate student you couldn’t do any of this stuff, right? It […]

Webinar: Uncover Epigenetic Signatures Faster using SureSelectXT Human Methyl-Seq

April 3, 2012

Agilent Technologies presented a Webinar back in March titled: Uncover Epigenetic Signatures Faster using SureSelectXT Human Methyl-Seq SureSelect is the most complete, flexible and proven Target Enrichment platform for Next Generation Sequencing. This presentation highlights features of the new SureSelect SureSelectXT Human Methyl-Seq kit including: • Reduced bias compared to existing Methylation methods • Comprehensive […]

ChIP-String Ties Down Chromatin Regulator Analysis

March 22, 2012

There are hundreds of chromatin regulators (CRs) out there, and yet we know so little about them other than that they control chromatin structure and function through interactions with histone mods. To help tie down the CR rules of engagement, some handy scientists developed the ChIP-string assay to provide a snapshot of several CRs in […]

Influenza Dodges Antiviral Response with Histone Disguise

March 22, 2012

Imitation is the sincerest form of flattery, they say. But instead of flattery, the influenza virus (and maybe many other viruses) imitates histones to make people sick. That kind of flattery we could do without. Researchers in NY and the U.K. discovered that influenza A (H3N2)—one of the strains that cause seasonal flu outbreaks—hijacks the […]

ChIP and Discs: Porvair’s Chromatrap® ChIP Kits Break through the Noise

March 22, 2012

Over the last decade, the ChIP process has seen more enhancements than the Orange County Housewives. Improved antibodies, beads, and fine-tuned buffers—they’ve all ChIP’d in to take this useful method primetime in labs all over the globe. But there’s always room for improvement. Turning Up the Pull Down for Small Sample ChIP Some of the […]

Bivalent PREs Protected by Perfect Timing

March 21, 2012

There’s no substitute for good timing. It’s a trait that can keep you out of a dangerous situation, or make you look good on the dance floor. But for cells it’s also critical for maintaining epigenetic states during replication. Italian researchers at the IRCCS Santa Lucia Foundation recently identified a critical time window right before […]

Webinar: Global and Locus-Specific 5-hmC Detection

March 21, 2012

New England Biolabs is hosting a free webinar titled: Global and locus specific 5-hydroxymethylcytosine detection and quantification Tues. March, 27th 2012 at 9am PDT It will discuss simple and quick enzymatic methods for global, as well as sequence-specific, determination of both DNA modifications throughout various genomes. T4 phage B-glucosyltransferase has emerged as the enzyme of […]