Comparing Methylomes Reveals Evolutionary SecretsSeptember 28, 2011Your mother always told you never to compare yourself with others, but in the methylation game, comparisons can reveal lots of cool info. Researchers now report that by comparing the methylomes of eight species, they found out that the placement of the H3K36me3 mark in Drosophila actually predicts where DNA methylation happens in other invertebrates. […]
Oh, the Horror! Commercial RTs Create False-Positive ncRNA DetectionSeptember 16, 2011With Halloween coming soon, we usually expect some visits from goblins, ghosts, and other creepy creatures who aren’t really what they seem. Now, researchers warn that using commercial reverse transcriptase (RT) might give you another sort of ghastly scare—you might think you’re detecting antisense non-coding RNA (ncRNA) when it isn’t even there. With so much […]
Epigenetic Instability Passes DNA Methylation Variation on to HeirsSeptember 15, 2011There are loads of things we’d hope to inherit from our parents, like intelligence, good looks or maybe even the family fortune, but we’re pretty sure altered DNA methylation wouldn’t make the list. No use worrying about that, though, since we can’t do much about it…and how often does that really happen anyway? A group […]
Podbat Let’s You Fly Through Epigenomic AnalysisSeptember 14, 2011How much would you pay to be able to analyze epigenomic data sets for multiple modifications, from various sources and different experiment types simultaneously? Before you answer, check out this new software tool, Podbat (Positioning database and analysis tool) that lets you do all of that and more…for free! When we first heard the name, […]
DNA Methylation Not So Identical in Schizophrenic TwinsSeptember 14, 2011Monozygotic (MZ), or identical, twins may seem like exact carbon copies of each other, but recent work has shown that epigenetic variation between them is common, even though they share an identical genome. Sometimes these small but significant epigenetic differences are suspected to lead to very different outcomes when it comes to psychiatric disorders like […]
Imprinted Brain Theory with Dr Christopher BadcockSeptember 13, 2011Dr. Christopher Badcock explains key epigenetic concepts of the Imprinted Brain theory and how it might change the way we think about mental disorders. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. Imprinted Brain Theory Well, […]
DNA Methylation in Stem Cell Pluripotency with Dr Louise LaurentSeptember 13, 2011Dr. Louise Laurent discusses DNA methylation patterning in the pluripotent state. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. This video was made possible by epigenetics supporters at Zymo Research. DNA Methylation in Stem Cell Pluripotency So […]
Epigenetics in Autism-Spectrum Disorders with Dr Janine LaSalleSeptember 13, 2011Dr. Janine LaSalle covers the epigenetics involved in autism-spectrum disorders. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. Epigenetics in Autism-Spectrum Disorders I’ll start with saying I kind of joked that I’ve been in epigenetics before […]
Bisphenol A (BPA) and the Epigenome with Dr Dana DolinoySeptember 13, 2011Dr. Dana Dolinoy discusses how early life exposures to environmental exposures like bisphenol A can impact the epigenome. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. This video was made possible by support from epigenetics fans […]
Epigenetics and Transgenerational Inheritance with Dr Michael SkinnerSeptember 13, 2011Dr. Michael Skinner lays down how environment exposures can impact epigenetics and generations to come. This short take was shot during a break at Keystone Symposia’s meeting on Environmental Epigenomics and Disease Susceptibility held in March 2011 in Asheville, North Carolina. Epigenetics and Transgenerational Inheritance I’ve been a researcher in the area of reproductive […]