epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

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Evolution of Advanced Sequencing Timeline

February 7, 2014

In a few short years. advanced sequencing has become nearly ubiquitous. Here we provide a history of how emerging sequencing technologies have driven epigenetic research and understanding.

Capture-C Catches Chromatin Contortions

February 5, 2014

Chromosome Conformation Capture (3C) is a cool technique that has lead to more spin-offs than the CSI TV franchise. This technique has been used at enhancers, silencers, boundary elements, and promoters at the individual loci level. But now a cunning team of researchers from Oxford University (UK) have just shown how to take it to an ‘omic level’. Here’ […]

World’s First CRISPR Monkeys

February 5, 2014

The Crispr/Cas9 genetic engineering system has gotten a lot of buzz lately for its potential in epigenetic editing and now a team of researchers in China have just made a huge breakthrough, using the technique to create genetically engineered monkeys. The scientists approach was to inject an engineered bacterial immune system (known as CRISPR/Cas9) into one-cell-stage […]

Zymo-Spin™ ChIP Kits Give Chromatin Immunoprecipitations the Run-around

February 5, 2014

After an extensive development and beta-testing process, the innovators at Zymo Research have unveiled the new Zymo-Spin™ ChIP Kit, which provides a whole new twist to standard chromatin precipitations. Special Discount to EpiGenie Readers: Get 20% OFF and a free “Blame It On My Epigenetics” T-shirt with every purchase of Zymo-Spin™ ChIP Kit (Catalog No. […]

Three Dimensional Chromatin & DNA Replication with Dr. David Gilbert

February 3, 2014

Dr. David Gilbert discusses the ins and outs of 3-D chromosome folding, DNA replication and the highly dynamic cell nucleus. 3-D Chromatin and DNA Replication There’s no question. The thing that I’m most excited about is the uncanny alignment between three dimensional chromatin confirmation maps and replication timing. The alignment is the greatest alignment that […]

The New Players in Epigenetic Reprogramming with Dr. Wolf Reik

February 3, 2014

Dr. Wolf Reik discusses the latest advances in epigenetic reprogramming, and what those new discoveries might lead to. The New DNA Methylation Landscape So it’s become apparent in the last two years, I guess, that there is this process of genome-wide epigenetic reprogramming which occurs naturally in germ cells, early embryo stem cells, et cetera, […]

Webinar: Mechanisms of Epigenetic Regulation in Stem Cells and Development

January 31, 2014

Dr. Alexander Meissner discusses the roles of epigenetic mechanisms in stem cells and development. Cytosine methylation in mammals is an epigenetic modification that is largely restricted to CpG dinucleotides and serves multiple critical functions including stable repression of target promoters, maintaining genomic integrity, establishing parent-specific imprinting patterns, and silencing endogenous retrotransposon activity. In somatic tissues, […]

Up In Smoke: Nicotine’s Epigenetic Consequences

January 22, 2014

As anyone who has tried to kick a pack-a-day cigarette habit can attest, nicotine is bad news. The jitters and surly attitude are bad enough, but according to a new investigation, fetal nicotine exposure also does some pretty insidious epigenetic damage. Daniel Hardy and a talented team Western University (Canada) have revealed a chromatin mechanism that […]

Methylation Separates Men from Monkeys

January 21, 2014

While we may share ‘99% of our genes’ with chimps, some cutting edge research has shown that when it comes to evolution, taking the stance of pure genetic determinism may just make a monkey out of you. The gene bringing today’s lesson? CNTNAP2, one of nature’s largest, with a role in human-specific language abilities and […]

The Next Steps in Chromatin Contact Analysis with Dr. Gerd Blobel

January 20, 2014

Dr. Gerd Blobel discusses emerging techniques for visualizing the interactions of RNAs and chromatin. The Future of Chromatin Contact Analysis So there are other approaches that people are taking, which is: you use FISH, for example, Fluorescent In Situ Hybridization. And this is a method that can be used to validate interactions that have been […]

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Epigenetics and ncRNA Headlines

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