epigenetics

Epigenetics and ncRNA Headlines

Get all the latest highlights from the literature and special features covering trending epigenetics, ncRNA, and gene regulation research.

Search Articles

Get the Lead Out of Your Epigenome

October 1, 2013

What’s mainly orange, sometimes a little black, and usually obese? Congratulations if you guessed Agouti (Avy) mice! (And you may want to consider spending less time in a vivarium) These chubby little creatures are well established as environmental epigenetics models because a number of environmental exposures are known to alter DNA methylation at the Avy […]

Charting Where Noncoding RNA Transcription Kicks Off

September 24, 2013

While ‘Dark Matter’ is thought to constitute roughly 85% of the cosmos, our genomic dark matter (i.e. noncoding RNAs) makes up an even larger portion (~95%) of our genetic content. Leaving the vastness of outer space to astrophysicists, Dr. Bryan Venters and Dr. Franklin Pugh at Pennsylvania State University focused on creating a map of […]

Trinucleotide Repeat (TNR) Disease Cheat Sheet

September 16, 2013

Trinucleotide repeat (TNR) diseases are some of the latest disorders to be linked to epigenetic state. So Dr. Marguerite Evans-Galea and colleagues at the Murdoch Childrens Research Institute and The University of Melbourne, wrote up this review to act as a sort of cheat sheet for the mounting evidence of epigenetic mechanisms in TNR. This […]

Webinar: Epigenomics – One Molecule at a Time with Dr. Paul Soloway

September 16, 2013

Dr. Paul Soloway, PhD discusses his latest work on technologies that enable the interrogation of epigenetic marks on a single molecule. **this webinar is no longer available** Epigenomic analyses are used for many applications, including discovering gene regulatory mechanisms; characterizing non-genetic transmission modes of adaptive and disease traits; identifying and detecting disease biomarkers; and for […]

Zymo ChIP DNA Clean & Concentrator™: A New Twist on Chromatin Immunoprecipitation

September 10, 2013

If you’re one of those researchers who has been avoiding ChIP experiments like the plague because of the aggravating low yields and poor quality ChIP DNA associated with traditional ChIP protocols, then it’s time to give the ChIP DNA Clean & Concentrator™ (ChIP DCC™) Kit from Zymo Research a whirl. The ChIP DCC™ is a […]

Mind Games: Sorting Out Brain Cell-type Specific Methylation

September 10, 2013

The human brain is the prime example of “highly specialized and diverse functions arising from the same genetic program.” But that comes at steep price. Our most complex organ is, well…very complex. Not only do it’s epigenetic marks constantly change both spatially and temporally but it’s also mainly and almost equally composed of two very […]

Priming Cancer Therapies with Epigenetics with Dr. Peter Jones

September 9, 2013

Dr. Peter Jones of the Norris Comprehensive Cancer Center at USC discusses the positive impact epigenetic therapies are having in the clinic. Priming Cancer Therapies with Epigenetics with Dr. Peter Jones Well, I think the thing that excites me the most is the increasing successes of epigenetic therapies in the clinic. And so I […]

Decoding the Molecular Mechanisms of lncRNA XIST

September 6, 2013

Fast on the heels of a major epigenetic engineering breakthrough revealing that XIST can help treat the symptoms of Down’s syndrome, Dr. Carolyn Brown (University of British Columbia) and crew sought to find out exactly what’s going on at the molecular level with this complex lncRNA. Their experimentation started with they hypothesis that “long ncRNAs […]

Stem Cell Conference Highlights Timeline

September 4, 2013

Stem Cells are a hot topic these days. Here we provide a history of epigenetic breakthroughs in this interdisciplinary field as told through our Conference Coverage.

Genome-wide and Gene-specific Analysis of DNA Methylation

September 3, 2013

EpiGenie recently reviewed the text Epigenetics by Jorg Tost. Here is a more in depth summary of one the chapters provided courtesy of JA Gill who is a molecular biologist at NOAA in the Northwest Fisheries Science Center, to give you a little sneak peek into what the whole book is all about: Methods for […]