Pol II Transcription Slows at 5-Formylcytosines (5caC) and 5-Carboxylcytosines (5fC)July 31, 2012It’s summertime—a time when you just want to take things slow. Researchers now report that 5-formylcytosines (5fCs) and 5-carboxylcytosines (5caCs) like to slow things down, no matter what the season. They say that these mods put the brakes on RNA Pol II transcription and make it less specific. Sure, researchers have known about 5fC and […]
Exploring the Genotype-Chromatin Structure-Disease Risk ConnectionJuly 26, 2012Its easy to obsess over little details, and want to understand every nuance of a subject that you’re passionate about, but sometimes it’s helpful to step back and get a broader perspective on what you’re working on. This review article from Richard Meagher and Kristofer Müssar at the University of Georgia does just that by […]
More Epigenomic Differences Found in Twins?July 24, 2012Twins may look alike, and even share identical genomes, but according to new studies, their epigenomes can be surprisingly different. Examination of the DNA methylation patterns in sets of twins revealed that early environmental conditions can alter epigenomes, and have a big impact on individual variability. A research effort headed up by Jeff Craig and […]
Guide: Quick Tips for ChIP BeginnersJuly 17, 2012 At Abcam we run quite a few ChIP assays and we interact with customers that run even more than us. Lately, we’ve noticed that more researchers are turning to ChIP for the first time as gene regulation studies continue to grow. So we thought we’d share a couple of quick tips for various aspects of […]
Pushing the Technology Frontier in Epigenetics Research with Dr. Andrew FeinbergJuly 16, 2012Dr. Andy Feinberg discusses what technology advances are needed in the field of epigenetics. This interview was shot on campus at Johns Hopkins University. This video was brought to you by epigenetics supporters at EMD Millipore Single Cell Analysis One of the areas I think is going to be really important is single-cell analysis. […]
