How a Histone Deacetylase-Regulated “Kiss” Controls the Timing of Sexual DevelopmentNovember 19, 2018“It started out with a kiss. How did it end up like this? It was only a kiss, it was only a kiss” – The Killers clearly didn’t foresee the consequences of a meeting of lips; however, a new study into the links between nutrition and mammalian sexual development now suggests that a histone deacetylase-regulated […]
If at First You Don’t Succeed, Try, Try Tri-CNovember 13, 2018It’s easy to think that at this point, science has it all figured out. We’ve developed genome-wide techniques to look at chromosome structure in many different contexts: from mapping chromatin interactions (Hi-C), to observing DNA-RNA interactions (SPRITE), and even identifying higher-order DNA structures (GAM). Unfortunately, none of these techniques have the resolution to look at […]
Smooth as Silc1: A ncRNA Lnc to Nerve RegenerationNovember 6, 2018When it comes to nerve damage, the mammalian peripheral nervous system (PNS) is arms and legs ahead of the central nervous system (CNS) in its ability to regenerate damaged neurons. While neuroscientists already knew that the PNS has an innate ability to express pro-regenerative transcription factors after injury, a new paper has the nerve to […]
Extra! Extra! Read All About It! – Study of Extra-Telomeric Roles of hTR Uncovers Histone mRNA-Mediated Telomere Homeostasis!November 6, 2018When it comes to our telomeres, we are often left with the feeling that a little bit extra is better. However, a new article which just crossed our paths had a little bit of “extra” that turned our heads: a study of the extra-telomeric functions of the human telomerase RNA component (hTR). hTR contains a […]
Histonagram: C. elegans Sperm Carry a Histone Memory of Spermatogenesis and OogenesisOctober 31, 2018While Instagram may have replaced the Polaroid, some age-old memories just can’t be shaken. Thankfully, the sperm epigenome of C. elegans has conjured up the latest social media trend, the histonagram: a histone based memory of spermatogenesis and oogenesis that shapes offspring fertility. Although C. elegans differ from us humans in that they don’t make use […]