Wake Up and Don’t Smell the Coffee! – How SARS-CoV-2-Induced DNA Methylation Impacts Your Sense of SmellJuly 18, 2022While many researchers have woken up, smelled the coffee, and realized the importance of epigenetic alterations in response to SARS-CoV-2 infections, many patients recovering from COVID-19 have been left unable to enjoy the olfactory joy of their first cup of java as each new day dawns. Now, well-caffeinated researchers led by Maria Lerm at Linköping […]
Anchor-based Bisulfite Sequencing Sets Sail to Explore the DNA Methylome!July 10, 2022The anchor is a crucial part of any seaworthy ship of exploration, and after setting sail from your local CpG island, you’ll be glad you stowed anchor-based bisulfite sequencing (or ABBS) to keep your DNA methylation voyages firmly anchored to new and exciting regions of the methylome. Anchor-based bisulfite sequencing, which comes to you from […]
Location, Location, Location! – How Site-specific mRNA ac4C Acetylation Impacts TranslationJune 29, 2022Where you spend your time away from work – a lake-side cottage far from the hustle and bustle or a party pad in the bohemian part of town – is a crucial decision. Now, new research on roaming RNAs demonstrates that when you call the epitranscriptome your home, the age-old rule “location, location, location” also […]
Now In Print! – New Technologies Leave their Mark on Imprinting Control RegionsJune 19, 2022Genomic imprinting typically lets our parents leave their mark on our genomes; however, new technological advances are now allowing us to leave our mark on imprinting! The first of our epigenetic exposés that went into print reports on how multiple modalities uncovered complex epigenetic crosstalk that regulates allele-specific gene expression at potential imprinting control regions […]
Dr. Steve Chan: The Epigenetic Regulation of Breast CancerJune 9, 2022Using unbiased ChIP-Rx analyses to discover a novel role for CTR9 in the epigenetic regulation of PRC2 subtype switching in breast cancer Our colleagues at Proteintech hosted a webinar from Dr. Steve Chan from The University of Wisconsin-Madison, who reviewed their recent paper “The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 […]