Gut Microorganisms Make Epithelial HDAC3 Work to their RhythmOctober 7, 2019While many of us prefer the sound of silence, others feel the need to inject a little rhythm into their everyday lives; but how do you do it? Spinning a few records at home, moving to the beat at Samba lessons, or do you use the microorganism-mediated activity of Hdac3 in your gut?! While researchers […]
Webinar: The Epigenetics of the Exposome and Aging – Paul G. ShielsOctober 2, 2019Don’t miss this great webinar detailing some of the latest discoveries about the role of epigenetics in aging. Aging results in a gradual and progressive loss of physiological functions and physical abilities over time. Overcoming the growing burden of age-related issues is one of the greatest challenges facing modern society. These issues are leading to […]
DNA Methylation Analysis Puts a Face to a Very Ancient NameOctober 1, 2019A long, long time ago, in a land far, far away (2014 at the Hebrew University of Jerusalem, Israel actually!) a team of researchers banded together under the leadership of Liran Carmel and David Gokhman. Rather than inventing the wheel or devising a strategy to capture wooly mammoth, the team developed a way to reconstruct […]
Sherlock Genomes: Stimulation Leaves Epigenetic Evidence Behind in NeuronsSeptember 30, 2019Even the most careful criminals leave some kind of evidence; a fingerprint or a strand of hair can be enough for a clever investigator to link them to the scene of the crime. Although it’s far from an open and shut case, new research in mice shows that the epigenome of neurons contains chromatin clues […]
The Tn5 Transposase Takes Single-cell ChIP-Seq to the Next LevelSeptember 18, 2019It’s never good to see someone lagging behind the rest, but while stepwise developments to single-cell chromatin immunoprecipitation and subsequent parallel sequencing techniques (ChIP-seq) have led to gradually improved yields and increased sensitivity with reduced numbers of cells since the first report of a single-cell ChIP protocol, we still lack widely-applicable and low-cost methods to […]
