DNA Methylation Deserts: Hot Spots for Structural Genomic MutationsMay 23, 2012Deserts typically stir up images of desolate landscapes sprinkled with cacti, but according to a new report, ‘methylation deserts’, the 1% of the genome with the lowest occurrence of DNA methylation, are actually fertile ground for structural genomic mutations. A research group from the Baylor College of Medicine knew that the human genome contains many loci […]
Enhancers Set the Stage for Stem Cell Differentiation during EmbryogenesisMay 23, 2012It’s amazing to think that we all started out as one cell with DNA from our parents inside. Now, researchers in Spain and the Netherlands say that they have a better idea of how development happens—and enhancers are showing them the way by pointing out active genes. The researchers knew that active enhancers are marked […]
ChIP Enrichment Gets Solid (Phase)May 16, 2012The application of chromatin immunoprecipitation (ChIP) in epigenetics research is expanding constantly. Lately it seems that every last aspect of the ChIP process from antibody validation and DNA shearing to purification is being fine-tuned by experts worldwide. One of the latest upgrades to the ChIP process improves chromatin capture and cleanup. Over the years researchers […]
Single Molecule Epigenetic Analysis with Dr. Paul SolowayMay 15, 2012Dr. Paul Soloway discusses the limitations with some of the main methods used in epigenetics research and shares a glimpse into what the next generation of tools will look like. This interview took place at the Keystone Symposia’s Epigenomics and Chromatin Dynamics joint meeting in January, 2012. Getting Past ChIP and Bisulfite Applications So, chromatin […]
Conference Trends: Nutrition in EpigeneticsMay 15, 2012Conferences provide an up-to-the-minute look at what’s going on inside epigenetics labs all over the world. By tuning into our conference coverage, we’ve tagged diet and nutrition as an important trend to follow in epigenetic research. Here’s a look at some trendy examples in our Conference Highlights from the last year or so. Differentially Methylated […]
