Improvements in DNAm-Based Colorectal Cancer Screening Has Community BEAMingAugust 17, 2009We know how important it is to get colorectal cancer screenings, but they rank up next to taxes on the fun factor. In fact, we’d much rather have our doc run our blood or fecal sample through the new methyl-BEAMing (Beads, Emulsion, Amplification and Magnetics) technology developed by the DNA gurus of Vogelstein et al. […]
Famine, Conception, and MethylationAugust 13, 2009Over the years many celebrities and well doers worldwide have drawn our attention to those in need of aid and nourishment. Whether you attended Harrison’s Concert for Bangladesh (not likely given the median age our audience), or remember singing along with Lionel Richie to the multi-platinum “We Are the World,” single (more likely) or maybe […]
RNA Pol II: The Hardest Working Polymerase in EpigeneticsAugust 13, 2009Stop us if you’ve heard this one before: new research shows RNA Pol II is a key player in an epigenetic mechanism. Lately, RNA Pol II seems to be in the headlines more than the Jonas Brothers, only with fewer screaming, teen fans. Recently we featured a paper suggesting that non-coding tiRNAs are formed through […]
Vidaza® and Entinostat Combo; A Potential Lung Cancer TherapyAugust 6, 2009Some things always seem better in combos: beer & pizza, SpongeBob & square pants… Soon, we may need to add Vidaza® & entinostat to that list. At the recent American Society of Clinical Oncology annual meeting, researchers from Johns Hopkins Medical Institute and the Lovelace Respiratory Research Institute reported that the combination of Vidaza® (5-azacitidine) […]
Mir-143 Slacks Off, Leaving DNMT3A To Run Wild In Colorectal CancerAugust 6, 2009We like to think of epigenetics in terms of distinct areas like chromatin, DNA methylation and non-coding RNA (heck, we’ve even divided up the EpiGenie website that way), but more and more evidence is blurring the lines and showing us how these overlap. A recent publication from researchers at The Chinese University of Hong Kong […]
