Getting RIPped: miRNA Target ID Workout DeliversSeptember 9, 2009As former bodybuilder turned California Governator, Arnold Schwarzenegger, once said, “Great abs are made in the kitchen…” That may be, but when it comes to epigenetics research, great abs are made by great labs and suppliers, and they’re put to work in immunoprecipitation applications like RIP Chip. Recently, Anke van den Berg and colleagues at […]
Sorting Out Epigenetic Marks NanostyleSeptember 7, 2009Cornell molecular geneticist Paul Soloway wants to know where epigenetic marks coincide – and not just in which patients, or in which tissues, or even in which cells, but on which individual stretches of chromatin. He and co-PI Harold Craighead, an engineering physicist at Cornell, have an Epigenomics Roadmap grant that will help them find […]
miRNA Functional Analysis Unleashed with Ambion® Anti-miR™ miRNA Inhibitors and Pre-miR™ miRNA PrecursorsAugust 28, 2009So you’ve just wrapped up a bunch of miRNA profiling experiments and now it’s time to get functional. Like any researcher studying miRNA you probably lie awake at night asking yourself: What is it targeting? With what pathways is it involved? What happens when there is too much, or not enough of it? To help […]
Chromatin Structure: More Biasing Than A Political Talk ShowAugust 26, 2009If you watch television news these days, you can spot bias a mile away. Well, we can’t do much about shoddy journalism, but a new report from scientists at UC Berkeley, led by Michael Eisen, calls attention to some bias we can fix; the kind caused by the structure of chromatin in ChIP experiments. The […]
Bioinformatics Brawn Links Histone Mods To mRNA SplicingAugust 25, 2009With terabytes of data streaming off sequencers nowadays, there’s heaps of data available that is begging to be mined. You don’t always have to run your own wet lab experiments either, if you know where to look. We know most bosses or PIs out there will probably resist cutting you loose to Starbuck’s to “crunch […]