Epigenetics 101: You Can’t Always Blame Your Parents with Alberto PerezDecember 17, 2013EpiGenie reader Dr. Albert Perez lays out some of the basic concepts behind epigenetics, and explains how being a red-head in Spain started him on a path to explore DNA and the epigenome.
DNA Methylation and Diet: You Are Also What Your Father AteDecember 17, 2013Freud famously blamed mothers for nearly everything, and when early epigenetic studies indicated that you are what your mom (and grandma and great-grandma) ate, it seemed to back him up. But when it comes to complex traits and environment, a new report from scientists at McGill University (Montreal) found that a father’s diet shapes a child too. […]
Webinar: Covering all the Bases with Genome-Wide 5-mC and 5-hmC SequencingDecember 17, 2013Covering all the Bases with Genome-Wide 5-mC and 5-hmC Sequencing By Dr Keith Booher, PhD. Manager of Epigenetic Services at Zymo Research Abstract: There is an ever-increasing appreciation for the remarkable ability of epigenetic modifications, such as the methylation of cytosines in DNA (5-mC), to respond to environmental cues and influence gene expression in biological […]
Tet1 Demethylation Wipes the Genomic Imprinting Slate CleanDecember 12, 2013The mechanisms surrounding genomic imprinting has always been a bit of black-box, especially when it comes to the erasure of paternal methylation patterns. A recent study led by Yi Zhang at the Boston Children’s Hospital has made a breakthrough in our understanding of imprinting, showing that Tet1 is a major part of the clean-up crew […]
Promega SIRT-Glo™ Assays Illuminate the Search for SirtuinsDecember 11, 2013Sirtuins (SIRTs) sure seem to getting around. These energetic class III HDAC enzymes have their fingerprints on everything from Alzheimer’s to Inflammation, generating enough spotlight (and even a little controversy) to make even Kanye West a feel little jealous. Promega’s new SIRT-Glo™ Assays and Screening Systems are the latest tool to help researchers study the […]
