Go Small with EpiSeeker Bisulfite Modification Kit – Whole CellFebruary 14, 2013In DNA methylation studies, some of the biggest findings come in the smallest sample sizes. But if you’re not using the right bisulfite conversion system, potential gold in samples like tissue biopsies, microdissected samples, and stem cells might be off limits. That is of course, unless you’re using a slick system like Abcam’s Bisulfite Modification […]
Tackling Heterogeneity with DNA MethylationFebruary 12, 2013Heterogeneity adds value to our culture in numerous ways, but when it comes to analyzing large-scale case/control studies with blood, heterogeneity can be more frustrating than a Rubik’s Cube. Since blood is an easy-to-get, relatively noninvasive specimen, it’s ideal for disease diagnosis and for monitoring the effectiveness of treatments. Scientists have reported that DNA methylation […]
EpiGenie Guide: ChIP Antibody ValidationFebruary 11, 2013If you can find a ChIP Grade or ChIP Validated antibody, then you’ve got a head start. But there’s no reason to stress if you can’t. Leave that for the data analysis part of your experiments (only kidding). A quick check of the spec sheet of any antibody can reveal lots of useful info. Here […]
EpiGenie Reviews: RNA Interference and Viruses – Current Innovations and Future TrendsFebruary 11, 2013RNA interference (RNAi) was first discovered in 1998 and has sparked new innovations and novel research tools for biological research ever since. RNAi has the scientific community buzzing because of it’s huge potential to tackle some of our most dreaded viral infectious diseases, like hepatitis C virus (HCV) and human immunodeficiency virus (HIV). But there […]
The Epigenetics of Organ TransplantationJanuary 31, 2013Dr. Daniel Salomon discusses the state of organ transplants, what obstacles exist, and how epigenetics might be central to improving long-term health in patients. The Challenges in Transplantation My background is in transplantation medicine, transplantation immunology. And my interests are to change the way we manage patients. There’s a huge series of challenges right […]
