Doubling Down on 5-hmC Profiling with Dual MeDIP from DiagenodeMay 11, 2011A year after 5-hydroxymethylcytosine’s (5-hmC) dramatic entrance into the epigenetics research scene, the research community has a long list of questions to ask about the 6th base. Investigations into 5-hmC were sidelined for most of the year due to the absence of methods to analyze it. Thankfully those helpless days are history as Diagenode just […]
Enrich Your DNA Methylation Experience with NEB’s EpiMark™ KitMay 4, 2011Do you dread launching your next DNA methylation study with the same old affinity reagents? Worried that it’ll take too much time, or that the specificity just won’t hack it? Then fret no more, because the latest EpiMark™ DNA Methylation Enrichment Kit from New England Biolabs is here to offer a much more fulfilling experience. […]
miRNAs: Masters of the Tumor MicroenvironmentMay 3, 2011We’ve all heard the slogans about how to lessen our impact on the environment: Reduce, Reuse, Recycle. But, what about the impact of microenvironments on us? Scientists have known for years that tumor growth is supported by the surrounding microenvironment, and now a group of Italian researchers have identified miRNAs as the masters that control […]
Race and Sex Major Players in Global DNA MethylationMay 3, 2011Lower global DNA methylation levels have been associated with genomic instability and cancer in humans, making it a great potential biomarker in peripheral blood. So scientists took a close look at the factors around global methylation levels and found that race and gender play a huge role. Researchers from Texas and New York measured the […]
Probing Placental EpigeneticsMay 3, 2011Ever since Tom Cruise publicly vowed to eat his newborn’s placenta a few years back, the “afterbirth” organ has gotten a bum rap. But recent evidence suggests that in addition to its long-recognized role in supplying oxygen and nutrients to the growing fetus, the placenta also influences fetal development through epigenetic mechanisms. Now a trio […]
