Epigenetic Editing Makes the (Neuronal) Connection Between C11orf46 and NeurodevelopmentJanuary 21, 2020Whether it’s our personal of professional lives, we’re told time and time again that making the right connection is key. It turns out that that’s also true for our brains; making proper neuronal connections early is make or break. Altered neuronal connections can cause neurodevelopmental disorders. Often, these disorders are associated with mutations in genes […]
When a Reader Goes Rogue: Mutant Chromatin Reader Alters Cell FateJanuary 17, 2020On the list of “first world problems”, having your tablet or e-reader break is certainly an annoyance; you might get stuck watching bad in-flight movies or have to wait a bit longer to see what happens in the big plot twist. But the story might be in the horror genre if it’s your histone reader […]
Retrotransposons LIT the Way for Genomic Imprinting During EvolutionJanuary 9, 2020It’s clear that humans and mice have taken very different evolutionary paths, but new research suggests that transcription from long terminal repeat retrotransposons (LTRs), which are endogenous retroviral elements that can induce DNA methylation in oocytes, may have acted as guiding lights along the forks in the road. Besides the obvious differences in size, furriness, […]
The Epigenomics of Non-Coding DNA Variants with Dr. Guillaume BourqueDecember 20, 2019Dr. Guillaume Bourque from McGill University discusses his lab’s bioinformatic research examining the epigenomics of non-coding DNA sequence variants at the 2019 joint CEEHRC/IHEC meeting.
The Epigenetics of T-Cell Development with Dr. Ellen RothenbergDecember 20, 2019Dr. Ellen Rothenberg from the California Institute of Technology discusses her lab’s research into the epigenetics of T-cell development at the 2019 joint CEEHRC/IHEC meeting.
