Sperm Epigenomics and Environmental Exposures with Dr. Sarah KimminsDecember 20, 2019Dr. Sarah Kimmins from McGill University discusses her lab’s research into sperm epigenomics at the 2019 joint CEEHRC/IHEC meeting.
MeCP2 on the Brain: Repressing Transcription of Long Highly Methylated GenesDecember 17, 2019It seems that everyone has MeCP2 on the brain – as evidenced by its starring role in two new Molecular Cell papers – but it’s in your brain too! The MeCP2 protein is essential for neuronal function and consistent with this, loss-of-function mutations in MeCP2 cause the neurodevelopmental disorder Rett syndrome. Unfortunately, because MeCP2 acts […]
Stressed Out Histone Modifications Mediate Lifespan ExtensionDecember 14, 2019While we have always thought of stress as something that will send us an early grave, fascinating new findings now suggest that early life stress may actually prevent such a dreaded fate. New research from the stress-resilient team in the lab Ursula Jakob (University of Michigan, Ann Arbor, MI, USA) has now linked increased levels […]
Epigenetic Couch Potatoes: Running isn’t on the Resolution Radar of Rodents This Year Thanks to DNA MethylationDecember 11, 2019The year is coming to an end and you know what that means — it’s time to promise yourself that next year is your year to get fit. But if you’re one of the many who never quite live up to their lofty activity goals, don’t be too hard on yourself; your epigenetics may be […]
Cancer Cells Get in Shape Using Circular Extrachromosomal DNA with Highly Accessible ChromatinDecember 3, 2019Cancer cells run rings around their normal counterparts in terms of proliferation, survival, migration, and aggressivity to devastating effect, but how do cancer cells get themselves “in shape” to allow for these strenuous activities? Previously, researchers led by Howard Y. Chang (Stanford University), Bing Ren, Vineet Bafna, and Paul S. Mischel (University of California at […]
