Genome-Wide Methylation Sequencing Hits the Fast LaneFebruary 11, 2011Genome-wide DNA methylation sequencing hasn’t been much more than sci-fi reading for most labs. Sure there’ve been some great papers with really slick technologies, but many researchers just don’t have access to them. In many cases, no single lab can handle the complete experimental workflow from sample prep to data management/analysis, requiring collaborations with other […]
MethylC-Seq Delivers First Single Base Resolution Methylation Profiles of iPSCsFebruary 2, 2011There’s always something a bit “off” when you look at aging starlets who’ve had some work done. In the same way, researchers in California and Wisconsin recently found that induced pluripotent stem cells (iPSCs) generated from old somatic cells aren’t quite the same as youthful embryonic stem cells (ESCs)—the epigenetics are “off”. Sure, iPSCs and […]
Watch It: Sensitive 5-hmC Detection in ActionFebruary 1, 2011Hockey, Nascar, 5-hmC analysis…. Somethings are just better experienced in person. So if you’re in the market for pinning down 5-hmC in your studies, you’ll want to check out this short JOVE vid that show’s NEB’s EpiMark™ 5-hmC and 5-mC Analysis Kit tracking down 5-hydroxymethylcytosine levels in mouse Babl/C brain. Watch Video Click to view […]
ChIP-Seq Libraries Made Easy with NEBNext® ReagentsFebruary 1, 2011A wealth of answers exist within the world’s libraries. Shouldn’t the same be true for your ChIP-Seq library? Sequencing has catapulted the output of ChIP analyses to levels most researchers wouldn’t have dreamed of just a few short years ago, but the quality of all of that output depends on a number of factors, including […]
Take a Bite Out of Cancer with the Epigenetics DietFebruary 1, 2011What’s your idea of a perfect meal? Whether you’re into the In-N-Out burger, fries, and milkshake trifecta, or you’re more of a “cleanse” type, the epigenetics enthusiast in you will be interested in a recent review by Trygve Tollefsbol and colleagues that reveals that certain foods contain ingredients that may prevent and treat cancer. Although […]
